Plant Profile

Chamomile

Matricaria chamomilla
Family: Asteraceae  ·  Parts used: Flower  ·  Also known as: German chamomile, blue chamomile, wild chamomile, Scented Mayweed

The complete database record: 4 documented constituents, 11 pharmacological actions, 18 traditional / indicated uses, with 24 cited sources.

Botanical Description

Aromatic annual herb, 15-60 cm tall, with an erect, much-branched, hairless stem. Leaves are alternate and finely bi- to tripinnately divided into thread-like segments, giving a feathery appearance. Flower heads are small daisy-like composites, 1-2.5 cm across, with white ray florets that reflex sharply downward as the flower matures around a conical, hollow, yellow disc of tubular florets - the hollow, conical receptacle is a key feature distinguishing German chamomile from similar-looking daisies. The fruit is a tiny ribbed achene without a pappus.[1, 10]

Height: 15-60 cm
Habit: Erect, much-branched, aromatic annual herb
Leaves: Alternate, finely 2-3-pinnately divided into thread-like segments
Flowers: Small daisy-like heads with downward-reflexed white ray florets around a conical hollow yellow disc
Stem: Erect, much-branched, hairless
Root: Slender taproot
Fruit: Tiny ribbed achene, no pappus
Flowering Period: May-August

Habitat & Distribution

Native to Europe and western Asia and now naturalised worldwide, growing on disturbed, sunny ground - arable field margins, waste places, roadsides and sandy or loamy soils; widely cultivated as a medicinal crop.[1, 6]

Harvesting

Flower heads are hand- or machine-harvested at full bloom, when the ray florets are horizontal and just beginning to reflex, then dried quickly at low temperature and out of direct light to preserve the volatile oil.[6]

Parts: Flower heads
Season: Late spring to summer, at full bloom

Key Constituents

Essential oil (alpha-bisabolol, chamazulene)[1, 6]

The volatile oil, concentrated in the flower head, gives chamomile its characteristic blue colour (chamazulene) and much of its anti-inflammatory activity (alpha-bisabolol).

Essential (volatile) oilAlpha-bisabololChamazulene
Flavonoids (apigenin, quercetin, luteolin, rutin)[10]

Apigenin is considered a key contributor to chamomile's sedative/anxiolytic activity via GABA-A receptor binding.

ApigeninQuercetinLuteolinRutinFlavonoids
Coumarins[6]

Minor constituents (e.g. herniarin, umbelliferone) contributing to the mild antispasmodic action.

Coumarins
Mucilage polysaccharides[10]

Contribute to the soothing, demulcent effect on irritated mucous membranes.

MucilagePolysaccharides

Pharmacological Actions

Analgesic (pain relief)[12, 14, 16, 17, 18, 20]
Anti-inflammatory[1, 5, 6, 7, 10, 12, 16, 17, 18, 20]
Antimicrobial[1, 16, 17, 18, 20]
Antispasmodic[1, 5, 6, 14, 16, 17, 18, 20]

Antispasmodic (cramp easing)

Digestive aid[1, 5, 10, 16, 17, 18, 20]
Emollient / skin-soothing[16, 17, 18, 20]
Sedative / sleep support[1, 2, 3, 4, 7, 8, 10, 16, 17, 18, 20]
Vulnerary (wound healing)[16, 17, 18, 20]
Anxiolytic / calming[3, 8]
Antidepressant / mood support[11]
Antidiabetic (blood-sugar lowering)[13]

Traditional & Indicated Uses

Arthritis / joint pain[12, 17, 18, 20]Moderate · 5/10

inferred from anti-inflammatory action

Mechanistic Exclude Ids: REF-0079
Evidence: 5
Label: Arthritis / joint pain

more plants for arthritis / joint pain →detailed sources →

Back pain[17, 18, 20]Preliminary · 1/10

inferred from analgesic action

Mechanistic Exclude Ids: REF-0079, REF-2349, REF-2351
Evidence: 1
Label: Back pain

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Bloating[16, 17, 18, 20]Preliminary · 1/10

inferred from digestive action

Evidence: 1
Label: Bloating

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Bruising[17, 18, 20]Preliminary · 1/10

inferred from vulnerary action

Mechanistic Exclude Ids: REF-0079
Evidence: 1
Label: Bruising

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Eczema[16, 17, 18, 20]Preliminary · 1/10

inferred from emollient action

Evidence: 1
Label: Eczema

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Headache[17, 18, 20]Preliminary · 1/10

inferred from analgesic action

Mechanistic Exclude Ids: REF-0079, REF-2349, REF-2351
Evidence: 1
Label: Headache

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Indigestion[16, 17, 18, 20]Preliminary · 1/10

inferred from digestive action

Evidence: 1
Label: Indigestion

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Infection (general)[16, 17, 18, 20]Preliminary · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)

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Inflammation (general)[16, 17, 18, 20]Preliminary · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)

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Insomnia / sleeplessness[2, 17, 18, 20]Good · 7/10

inferred from sedative action

Mechanistic Exclude Ids: REF-0079, REF-1155, REF-1156, REF-1160
Evidence: 7
Label: Insomnia / sleeplessness

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Menstrual cramps[14, 17, 18, 20]Good · 7/10

inferred from antispasmodic action

Mechanistic Exclude Ids: REF-0079
Evidence: 7
Label: Menstrual cramps

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Muscle spasm[16, 17, 18, 20]Preliminary · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Muscle spasm

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Pain (general)[17, 18, 20]Preliminary · 1/10
Mechanistic Exclude Ids: REF-0079
Evidence: 1
Label: Pain (general)

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Skin irritation[16, 17, 18, 20]Preliminary · 1/10

inferred from anti-inflammatory action

Mechanistic Exclude Ids: REF-2349
Evidence: 1
Label: Skin irritation

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Wounds[16, 17, 18, 20]Preliminary · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds

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Anxiety[3, 8]Moderate · 6/10
Evidence: 6
Label: Anxiety

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Low mood / depression[11]Moderate · 5/10
Evidence: 5
Label: Low mood / depression

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Blood sugar / diabetes support[13]Moderate · 5/10
Evidence: 5
Label: Blood sugar / diabetes support

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Traditional Use & History

Chamomile is one of the most widely used medicinal herbs in the world, with a long traditional history as a mild digestive, calming and anti-inflammatory remedy - taken as a tea for indigestion, cramping, and restlessness or poor sleep, and applied topically for skin and mucous-membrane inflammation and wound healing. Modern reviews confirm anti-inflammatory, antispasmodic, sedative/anxiolytic and antimicrobial pharmacological activity supporting these traditional uses.[1, 6, 10]

Preparations

Infusion (tea)[6, 10]

Dried flower heads steeped in hot water, the classic way of taking chamomile for digestive complaints, mild anxiety and sleep support.

Essential oil[1]

Steam-distilled from the flower heads; a concentrated source of alpha-bisabolol and chamazulene, used mainly in topical and aromatherapy preparations.

Topical cream/compress[12]

Concentrated extract or infused oil applied to skin, or as a compress - a randomised controlled trial found a topical chamomile oil preparation effective for knee osteoarthritis pain.

Dosage

Infusion (tea)[16, 17, 18, 19, 20]

Traditional guidance and Duke (2002) suggest about 3 g of dried flower heads per cup of water, taken up to three times daily. Educational reference only, not a prescription.

Safety, Cautions & Contraindications

Safety note[16, 17, 18, 19, 20]Caution

Generally considered very safe when used as tea or topical preparations.Allergy risk: People allergic to ragweed, daisies, or other Asteraceae plants may react (itching, rash).Blood thinners: Chamomile may slightly enhance effects of anticoagulants-use large amounts cautiously.Pregnancy: Normal tea amounts are usually considered safe, but concentrated extracts should be used with caution.Topical use: Rare skin irritation in sensitive individuals.

Safety note[16, 17, 18, 19, 20, 21]Caution

Duke (2002) rates German chamomile (Matricaria chamomilla) highly for anti-inflammatory, antispasmodic, and wound-healing activities. The essential oil contains the potent anti-inflammatory compound alpha-bisabolol. Chamomile is Commission E approved for digestive complaints and topical wound care. Dose: 3 g dried flower heads per cup of water, three times daily. Alpha-bisabolol is noted as one of the most active natural anti-inflammatory compounds known. Caution: chamomile belongs to the Asteraceae family and can cause allergic reactions in individuals sensitive to ragweed, chrysanthemums, or related plants (Duke, 2002).

Safety note[16, 17, 18, 19, 20]Caution

Generally very safe. Rare allergic reactions in individuals sensitive to the Asteraceae family (ragweed, chrysanthemums). May cause contact dermatitis with topical essential oil use. Avoid very high doses in pregnancy. Well tolerated by children in appropriate amounts.

Safety note[16, 17, 18, 19, 20, 21]Info

Scented mayweed (Matricaria chamomilla) shares the same species as German chamomile (see German Chamomile entry above). Duke (2002) provides the same clinical support: Commission E approves it for dyspeptic complaints (orally) and skin and mucous membrane inflammation (topically). Anti-inflammatory, antispasmodic, and wound-healing activities are well-established (Duke, 2002).

Herb-Drug Interactions

Anticoagulants Antiplatelets[22]Caution
Mechanism: Chamomile contains natural coumarin constituents and has been linked in a case report to increased bleeding when taken with warfarin, so caution is advised when combining it with anticoagulant or antiplatelet drugs.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03
Sedatives Cns Depressants[8, 23, 24]Caution
Mechanism: Chamomile has calming, sedative effects (a randomised controlled trial found it reduces generalised-anxiety symptoms); taken with sedatives, sleeping tablets or other central-nervous-system depressants (including alcohol) it may add to drowsiness and slowed reactions.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03
Antidiabetics[13]Caution
Mechanism: Chamomile improved blood-sugar control (lower HbA1c and insulin resistance) in a trial in type 2 diabetes; combined with diabetes medicines it may add to blood-sugar lowering, so monitor blood sugar.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Herb-Herb Pairings

Valerian[24]

Chamomile and valerian are both traditional mild sedatives for restlessness and poor sleep; taken together they may enhance calming and sleep effects but also add to drowsiness.

Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03
Lemon balm[24]

Chamomile and lemon balm are both gentle calming herbs commonly combined for stress and sleep; used together their mild sedative effects may add up.

Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03
Passionflower[23, 24]

Chamomile and passionflower are both gentle calming, sleep-supporting herbs traditionally combined; used together they may reinforce each other's soothing, sleep-promoting effect.

Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Harvest Readiness

[15]

Part: flower
Signals: Pick the flowerheads when fully open, in early-to-mid summer.
Basis: traditional
Source Quote: The flowers are harvested when fully open and are dried for later use.
Species Confirmed: 1
Notes: PFAF (REF-3289); the flowerheads are picked when fully open (in flower June-July). Single lineage -> provisional.

External Identifiers

References & Sources

  1. El Mihyaoui, A., Esteves da Silva, J.C.G., Charfi, S., Candela Castillo, M.E. and others (2022) 'Chamomile (Matricaria chamomilla L.): A Review of Ethnomedicinal Use, Phytochemistry and Pharmacological Uses', Life, 12(4), pp. 479. doi:10.3390/life12040479 Meta-analysis / review
    https://doi.org/10.3390/life12040479
  2. Kazemi, A., Shojaei-Zarghani, S., Eskandarzadeh, P. and Hashempur, M.H (2024) 'Effects of chamomile (Matricaria chamomilla L.) on sleep: A systematic review and meta-analysis of clinical trials', Complementary Therapies in Medicine, 84, pp. 103071. doi:10.1016/j.ctim.2024.103071 Meta-analysis / review
    https://doi.org/10.1016/j.ctim.2024.103071
  3. Mao, J.J., Xie, S.X., Keefe, J.R., Soeller, I. and others (2016) 'Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial', Phytomedicine, 23(14), pp. 1735-1742. doi:10.1016/j.phymed.2016.10.012 Randomized trial
    https://doi.org/10.1016/j.phymed.2016.10.012
  4. Amsterdam, J.D., Li, Q.S., Xie, S.X. and Mao, J.J (2020) 'Putative Antidepressant Effect of Chamomile (Matricaria chamomilla L.) Oral Extract in Subjects with Comorbid Generalized Anxiety Disorder and Depression', Journal of Alternative and Complementary Medicine, 26(9), pp. 813-819. doi:10.1089/acm.2019.0252 Clinical study
    https://doi.org/10.1089/acm.2019.0252
  5. McKay, D.L. and Blumberg, J.B (2006) 'A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.)', Phytotherapy Research, 20(7), pp. 519-530. doi:10.1002/ptr.1900 Meta-analysis / review
    https://doi.org/10.1002/ptr.1900
  6. Dai, Y.L., Li, Y., Wang, Q., Niu, F.J. and others (2022) 'Chamomile: A Review of Its Traditional Uses, Chemical Constituents, Pharmacological Activities and Quality Control Studies', Molecules, 28(1), pp. 133. doi:10.3390/molecules28010133 Meta-analysis / review
    https://doi.org/10.3390/molecules28010133
  7. Miraj, S. and Alesaeidi, S (2016) 'A systematic review study of therapeutic effects of Matricaria recutita chamomile (chamomile)', Electronic Physician, 8(9), pp. 3024-3031. doi:10.19082/3024 Meta-analysis / review
    https://doi.org/10.19082/3024
  8. Amsterdam, J.D., Li, Y., Soeller, I., Rockwell, K. and others (2009) 'A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder', Journal of Clinical Psychopharmacology, 29(4), pp. 378-382. doi:10.1097/JCP.0b013e3181ac935c Randomized trial
    https://doi.org/10.1097/JCP.0b013e3181ac935c
  9. Park, S.H., Kim, D.S., Oh, J., Geum, J.H. and others (2021) 'Matricaria chamomilla (Chamomile) Ameliorates Muscle Atrophy in Mice by Targeting Protein Catalytic Pathways, Myogenesis, and Mitochondrial Dysfunction', The American Journal of Chinese Medicine, 49(6), pp. 1493-1514. doi:10.1142/S0192415X21500701 Preclinical
    https://doi.org/10.1142/S0192415X21500701
  10. Singh, O., Khanam, Z., Misra, N. and Srivastava, M.K (2011) 'Chamomile (Matricaria chamomilla L.): An overview', Pharmacognosy Reviews, 5(9), pp. 82-95. doi:10.4103/0973-7847.79103 Meta-analysis / review
    https://doi.org/10.4103/0973-7847.79103
  11. Amsterdam, J.D., Shults, J., Soeller, I., Mao, J.J., Rockwell, K. and Newberg, A.B (2012) 'Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study', Alternative Therapies in Health and Medicine, 18(5), pp. 44-49. Randomized trial
    https://scholar.google.com/scholar?q=Chamomile%20%28Matricaria%20recutita%29%20may%20provide%20antidepressant%20activity%20in%20anxious%2C%20depressed%20humans%3A%20an%20exploratory%20study
  12. Shoara, R., Hashempur, M.H., Ashraf, A., Salehi, A., Dehshahri, S. and Habibagahi, Z (2015) 'Efficacy and safety of topical Matricaria chamomilla L. (chamomile) oil for knee osteoarthritis: a randomized controlled clinical trial', Complementary Therapies in Clinical Practice, 21(3), pp. 181-187. doi:10.1016/j.ctcp.2015.06.003 Randomized trial
    https://doi.org/10.1016/j.ctcp.2015.06.003
  13. Zemestani, M., Rafraf, M. and Asghari-Jafarabadi, M (2016) 'Chamomile tea improves glycemic indices and antioxidants status in patients with type 2 diabetes mellitus', Nutrition, 32(1), pp. 66-72. doi:10.1016/j.nut.2015.07.011 Randomized trial
    https://doi.org/10.1016/j.nut.2015.07.011
  14. Niazi, A. and Moradi, M (2021) 'The effect of chamomile on pain and menstrual bleeding in primary dysmenorrhea: a systematic review', International Journal of Community Based Nursing and Midwifery, 9(3), pp. 174-186. doi:10.30476/ijcbnm.2021.87219.1417 Meta-analysis / review
    https://doi.org/10.30476/ijcbnm.2021.87219.1417
  15. Plants For A Future 'Matricaria chamomilla (German Chamomile)'. Available at: https://pfaf.org/user/Plant.aspx?LatinName=Matricaria+chamomilla Traditional / reference
    https://pfaf.org/user/Plant.aspx?LatinName=Matricaria+chamomilla
  16. European Medicines Agency (2015) 'European Union herbal monograph on Matricaria recutita L., flos'. Traditional / reference
    https://scholar.google.com/scholar?q=European%20Union%20herbal%20monograph%20on%20Matricaria%20recutita%20L.%2C%20flos
  17. Hoffmann, D (2003) 'Medical Herbalism'. Traditional / reference
    https://scholar.google.com/scholar?q=Medical%20Herbalism
  18. Padula, M.C (2006) 'Chamomile: industrial profiles'. Traditional / reference
    https://scholar.google.com/scholar?q=Chamomile%3A%20industrial%20profiles
  19. Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
    https://powo.science.kew.org
  20. Srivastava, J.K., Shankar, E. and Gupta, S (2010) 'Chamomile: a herbal medicine of the past with bright future', 3(6), pp. 895--901. doi:10.3892/mmr.2010.377 Traditional / reference
    https://doi.org/10.3892/mmr.2010.377
  21. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  22. Segal, R. and Pilote, L (2006) 'Warfarin interaction with Matricaria chamomilla', CMAJ, 174(9), pp. 1281-1282. doi:10.1503/cmaj.051191 Clinical study
    https://doi.org/10.1503/cmaj.051191
  23. Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
    https://doi.org/10.1002/ptr.8201
  24. Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
    https://doi.org/10.1177/1534735404265003

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Selected studies & references

Educational use only. This profile summarises traditional and scientific sources for reference. It is not medical advice and not a substitute for a qualified practitioner. Some plants carry safety cautions and drug interactions - always check before use.
This profile is assembled automatically from the Omnia Sana plant database, which we curate by hand. How this site is built.
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