Journal

Shiitake (mushroom)

July 2, 2026 · Omnia Sana
Lentinula edodes
Family: Omphalotaceae  ·  Parts used: Mycelium, Whole Plant  ·  Also known as: Shiitake, Chinese forest mushroom, black mushroom

Key actions

Anticancer (preclinical)Antidiabetic (blood-sugar lowering)AntimicrobialAntioxidantAntiviralImmunomodulator / immune support

Traditional & clinical uses, by strength of evidence

  • Blood sugar / diabetes supportModerate
  • Cardiovascular / heart healthModerate
  • Cold & fluModerate
  • Immune supportModerate
  • Infection (general)Moderate
  • Metabolic supportModerate
  • WoundsModerate

Selected studies & references

ReviewClinical features of shiitake dermatitis: a systematic review (2017)
ReviewAre mushrooms medicinal? (2016)
ReviewShiitake Mushroom Dermatitis: A Review (2016)
ReviewLentinus edodes: a macrofungus with pharmacological activities (2010)
RctCurrent findings, future trends, and unsolved problems in studies of medicinal mushrooms (2011)
PreclinicalLentinan and beta-glucan extract from shiitake mushroom, Lentinula edodes, alleviate acute LPS-induced hematological changes in mice (2023)
PreclinicalSelenium-containing polysaccharides from Lentinula edodes-Biological activity (2019)
PreclinicalLentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production (2017)

All 13 studies in the Knowledge Finder →

Educational use only. This profile summarises traditional and scientific sources for reference. It is not medical advice and not a substitute for a qualified practitioner. Some plants carry safety cautions and drug interactions — always check before use.

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