Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production

Ahn, H., Jeon, E., Kim, J.C., Kang, S.G. and others · Scientific Reports · 2017

Preclinical

Abstract

Lentinan from shiitake (Lentinula edodes) selectively attenuated AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokines through TLR4, characterising a complex immunomodulatory action of the mushroom beta-glucan.

Referenced for these plants

Chinese forest mushroom Shiitake Shiitake (mushroom)black mushroomLentinula edodes

How to cite

Ahn, H., Jeon, E., Kim, J.C., Kang, S.G. and others (2017) 'Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production', Scientific Reports, 7(1), pp. 1314. doi:10.1038/s41598-017-01462-4

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