Journal

Skullcap

July 2, 2026 · Omnia Sana
Scutellaria lateriflora
Family: Lamiaceae  ·  Parts used: Aerial parts (flowering herb)  ·  Also known as: American skullcap, Blue skullcap, Mad-dog skullcap

Key actions

Anxiolytic / calmingSedative / sleep support

Traditional & clinical uses, by strength of evidence

  • AnxietyModerate
  • Insomnia / sleeplessnessModerate
  • Nervous tensionModerate
  • StressModerate

Selected studies & references

ReviewTherapeutic potential of hypnotic herbal medicines: A comprehensive review (2024)
ReviewSafety and efficacy of herbal sedatives in cancer care (2004)
RctEfficacy and Tolerability of a Chemically Characterized Scutellaria lateriflora L. Extract-Based Food Supplement for Sleep Management: A Single-Center, Controlled, Randomized, Crossover, Double-Blind Clinical Trial (2025)
RctEfficacy and Tolerability of a Cistus x incanus L. and Scutellaria lateriflora L.-Based Chewing Gum on the Symptoms of Gingivitis: A Monocentric, Randomized, Double-Blind, Placebo-Controlled Clinical Trial (2024)
RctAmerican Skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers (2014)
RctAn investigation into the efficacy of Scutellaria lateriflora in healthy volunteers (2003)
PreclinicalBiotechnological strategies for controlled accumulation of flavones in hairy root culture of Scutellaria lateriflora L. (2023)
PreclinicalMolecular characterization of flavonoid biosynthetic genes and accumulation of baicalin, baicalein, and wogonin in plant and hairy root of Scutellaria lateriflora (2016)

All 15 studies in the Knowledge Finder →

Educational use only. This profile summarises traditional and scientific sources for reference. It is not medical advice and not a substitute for a qualified practitioner. Some plants carry safety cautions and drug interactions — always check before use.

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