Journal

Japanese knotweed

July 2, 2026 · Omnia Sana
Reynoutria japonica
Family: Polygonaceae  ·  Parts used: Leaf, Root, Stem  ·  Also known as: Asian knotweed, Hu Zhang

Key actions

Anti-inflammatoryAnticancer (preclinical)Antioxidant

Traditional & clinical uses, by strength of evidence

  • Inflammation (general)Good
  • Arthritis / joint painTraditional
  • Cardiovascular / heart healthTraditional
  • Skin irritationTraditional

Selected studies & references

ReviewReynoutria japonica Houtt for Acute Respiratory Tract Infections in Adults and Children: A Systematic Review (2022)
PreclinicalPhysicochemical and rheological characteristics of commercial Greek-style yogurt enriched with Polygonum cuspidatum roots or the P. cuspidatum beta-cyclodextrin inclusion complex (2025)
PreclinicalThe Possibility of Polygonum cuspidatum against Osteoarthritis based on Network Pharmacology (2024)
PreclinicalCitri Reticulatae Pericarpium-Reynoutria japonica Houtt. herb pair suppresses breast cancer liver metastasis by targeting ECM1-mediated cholesterol biosynthesis pathway (2023)
PreclinicalBioactive amides from Reynoutria japonica (2021)
PreclinicalNew phenolic glycosides from Reynoutria japonica (2020)
TraditionalPolygonum cuspidatum polysaccharide: A review of its extraction and purification, structure analysis, and biological activity (2024)
TraditionalAdvances for pharmacological activities of Polygonum cuspidatum (Reynoutria japonica) – A review (2023)

All 13 studies in the Knowledge Finder →

Educational use only. This profile summarises traditional and scientific sources for reference. It is not medical advice and not a substitute for a qualified practitioner. Some plants carry safety cautions and drug interactions — always check before use.

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