Plant Comparison

Lemon balm vs Peppermint

A side-by-side comparison of two medicinal plants - every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant ALemon balmMelissa officinalisLamiaceaeFull monograph →
Plant BPeppermintMentha × piperitaLamiaceaeFull monograph →

At a glance

Lemon balm and Peppermint: both belong to the Lamiaceae family; they share 8 indicated uses (arthritis / joint pain, bloating, indigestion, …); 5 pharmacological actions in common.

Lemon balmPeppermint
Constituents43
Pharmacological actions611
Indicated uses1113
Safety notes22
Cited sources2037
Indicated uses
Only Lemon balm
Cold & fluInsomnia / sleeplessnessLow mood / depression
Shared (8)
Arthritis / joint painBloatingIndigestionInfection (general)Inflammation (general)Menstrual crampsMuscle spasmSkin irritation
Only Peppermint
Back painHeadachePain (general)WoundsCognitive function
Pharmacological actions
Only Lemon balm
Sedative / sleep support
Shared (5)
Anti-inflammatoryAntioxidantAntispasmodicAntiviralDigestive aid
Only Peppermint
Analgesic (pain relief)AntimicrobialAnticancer (preclinical)AntifungalNeuroprotective / cognition supportGastroprotective

Evidence face-off - shared uses

ConditionLemon balmPeppermintVerdict
Arthritis / joint pain1/10n/aComparable evidence
Bloating1/105/10Stronger for Peppermint
Indigestion1/105/10Stronger for Peppermint
Infection (general)7/102/10Stronger for Lemon balm
Inflammation (general)1/10n/aComparable evidence
Menstrual cramps1/10n/aComparable evidence
Muscle spasm1/105/10Stronger for Peppermint
Skin irritation1/10n/aComparable evidence

Evidence scores (1-10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Rosmarinic acid and phenolic acids[4, 6]

The principal phenolic acid of lemon balm, associated with much of its antioxidant and antiviral activity.

Rosmarinic acid
Essential oil (citral, citronellal)[4, 10]

The volatile oil (geranial and neral, together called citral, plus citronellal) gives the characteristic lemon scent and has demonstrated anxiolytic activity.

Essential (volatile) oilCitral (neral / geranial)
Flavonoids[4]

Contribute to the antioxidant activity of the leaf.

Flavonoids
Triterpenic acids (ursolic acid, oleanolic acid)[4]

Minor constituents studied for anti-inflammatory activity.

Essential oil (menthol, menthone)[3]

Menthol is the dominant constituent of the leaf oil, responsible for the cooling sensation and much of the antispasmodic and analgesic activity.

Essential (volatile) oilMentholTerpenes / terpenoids
Rosmarinic acid and flavonoids (eriocitrin, luteolin)[9]

Phenolic antioxidants of the leaf.

Rosmarinic acidFlavonoidsLuteolin
Tannins[2]

Contribute mild astringency.

Tannins

Pharmacological Actions

Anti-inflammatory[4, 6, 13, 14, 15]
Antioxidant[4, 6, 7, 13, 14, 15]
Antispasmodic[6, 13, 14, 15]

Antispasmodic (cramp easing)

Antiviral[4, 6, 8, 13, 14, 15]
Digestive aid[6, 13, 14, 15]
Sedative / sleep support[1, 2, 4, 6, 7, 10, 13, 14, 15]
Analgesic (pain relief)[2, 5, 34, 35, 36]
Anti-inflammatory[1, 2, 3, 11, 34, 35, 36]
Antimicrobial[1, 2, 3, 8, 15, 27, 28, 30, 32, 34, 35, 36]
Antioxidant[1, 2, 3, 9, 11, 18, 20, 26, 30, 31, 34, 35, 36]
Antispasmodic[1, 4, 34, 35, 36]

Antispasmodic (cramp easing)

Digestive aid[1, 2, 4, 34, 35, 36]
Anticancer (preclinical)[11]
Antiviral[13, 14]
Antifungal[16, 27]
Neuroprotective / cognition support[20, 21, 22, 23, 24, 25]
Gastroprotective[29]

Traditional & Indicated Uses

Arthritis / joint pain[13, 15]Preliminary · 1/10

inferred from anti-inflammatory action

Mechanistic Exclude Ids: REF-0134
Evidence: 1
Label: Arthritis / joint pain
Bloating[13]Preliminary · 1/10

inferred from digestive action

Mechanistic Exclude Ids: REF-0134, REF-0194
Evidence: 1
Label: Bloating
Cold & flu[13, 15]Preliminary · 1/10

inferred from antiviral action

Mechanistic Exclude Ids: REF-0134, REF-1200
Evidence: 1
Label: Cold & flu
Indigestion[13]Preliminary · 1/10

inferred from digestive action

Mechanistic Exclude Ids: REF-0134, REF-0194
Evidence: 1
Label: Indigestion
Infection (general)[8, 13, 15]Good · 7/10

inferred from antiviral action

Mechanistic Exclude Ids: REF-0134
Evidence: 7
Label: Infection (general)
Inflammation (general)[13, 15]Preliminary · 1/10

inferred from anti-inflammatory action

Mechanistic Exclude Ids: REF-0134
Evidence: 1
Label: Inflammation (general)
Insomnia / sleeplessness[13, 14]Moderate · 5/10

inferred from sedative action

Mechanistic Exclude Ids: REF-0194, REF-1194, REF-1202
Evidence: 5
Label: Insomnia / sleeplessness
Menstrual cramps[13]Preliminary · 1/10

inferred from antispasmodic action

Mechanistic Exclude Ids: REF-0134, REF-0194
Evidence: 1
Label: Menstrual cramps
Muscle spasm[13]Preliminary · 1/10

inferred from antispasmodic action

Mechanistic Exclude Ids: REF-0134, REF-0194
Evidence: 1
Label: Muscle spasm
Skin irritation[13, 15]Preliminary · 1/10

inferred from anti-inflammatory action

Mechanistic Exclude Ids: REF-0134
Evidence: 1
Label: Skin irritation
Low mood / depression[2]Good · 7/10

Meta-analysis of clinical trials: lemon balm may improve depressive and anxiety symptoms, particularly in the acute setting; trials are few and heterogeneous.

Evidence: 7
Label: Low mood / depression
Arthritis / joint pain

inferred from anti-inflammatory action

Mechanistic Exclude Ids: REF-0004, REF-0100, REF-0163
Evidence: 1
Label: Arthritis / joint pain
Back pain

inferred from analgesic action

Mechanistic Exclude Ids: REF-0004, REF-0100, REF-0163, REF-1207
Evidence: 1
Label: Back pain
Bloating[35]Moderate · 5/10

inferred from digestive action

Mechanistic Exclude Ids: REF-0004, REF-0163
Evidence: 5
Label: Bloating
Headache[5]Good · 7/10

inferred from analgesic action

Mechanistic Exclude Ids: REF-0004, REF-0100, REF-0163
Evidence: 7
Label: Headache
Indigestion[35]Moderate · 5/10

inferred from digestive action

Mechanistic Exclude Ids: REF-0004, REF-0163
Evidence: 5
Label: Indigestion
Infection (general)[13]Preliminary · 2/10

inferred from antimicrobial action

Mechanistic Exclude Ids: REF-0004, REF-0100, REF-0163
Evidence: 2
Label: Infection (general)
Inflammation (general)

inferred from anti-inflammatory action

Mechanistic Exclude Ids: REF-0004, REF-0100, REF-0163
Evidence: 1
Label: Inflammation (general)
Menstrual cramps

inferred from antispasmodic action

Mechanistic Exclude Ids: REF-0004, REF-0100, REF-0163
Evidence: 1
Label: Menstrual cramps
Muscle spasm[35]Moderate · 5/10

inferred from antispasmodic action

Mechanistic Exclude Ids: REF-0004, REF-0163
Evidence: 5
Label: Muscle spasm
Pain (general)[35]Moderate · 5/10
Mechanistic Exclude Ids: REF-0004, REF-0163
Evidence: 5
Label: Pain (general)
Skin irritation

inferred from anti-inflammatory action

Mechanistic Exclude Ids: REF-0004, REF-0100, REF-0163
Evidence: 1
Label: Skin irritation
Wounds

inferred from antimicrobial action

Mechanistic Exclude Ids: REF-0004, REF-0100, REF-0163, REF-1210, REF-3041
Evidence: 1
Label: Wounds
Cognitive function[21, 23, 24]Preliminary · 2/10

Peppermint/Mentha showed acetylcholinesterase inhibition (cognition-relevant, preclinical).

Mechanistic Exclude Ids: REF-3046
Evidence: 2
Label: Cognitive function

Safety, Cautions & Contraindications

Safety note[13, 14, 15]Caution

Generally very safe for adults. Theoretically may interact with thyroid medications and sedatives. Avoid high therapeutic doses during pregnancy. Long-term safety data beyond a few months is limited.

Safety note[13, 14, 15, 16]Info

Duke (2002) does not include a dedicated entry under 'Lemon Balm' or 'Melissa' in the Handbook of Medicinal Herbs, Second Edition.

Safety note[34, 35, 36]Caution

Generally very safe. Essential oil should not be applied to the face or chest of infants or children - menthol can cause respiratory depression. Avoid enteric-coated capsules if taking antacids or acid-suppressing drugs. May worsen GERD by relaxing the lower oesophageal sphincter. Avoid in bile duct obstruction and gallstones.

Safety note[34, 35, 36, 37]Caution

Duke (2002) rates peppermint as +++ with clinical evidence (score 2) for antispasmodic activity, consistent with Commission E approval for IBS (irritable bowel syndrome) using enteric-coated peppermint oil capsules. Enteric-coated peppermint oil is one of the most clinically validated herbal treatments for IBS, reducing abdominal pain and spasm. Dose: 0.6 ml enteric-coated oil two to three times daily between meals (for IBS); 1.5–3 g dried leaf as tea three times daily for digestive complaints. Peppermint should not be applied near the face or nostrils of infants and small children (risk of laryngospasm from menthol). Contraindicated in cholelithiasis (gallstones) (Duke, 2002).

External Ids

Gbif: 5341501
Wikidata: Q148396
Gbif: 8707933

Botanical Description

Perennial herb, 30-70 (up to 150) cm tall, with square, branched, hairy stems typical of the mint family. Leaves are opposite, ovate to heart-shaped with a toothed margin, wrinkled and softly hairy, releasing a strong lemon scent when crushed. Small, pale yellow to white, two-lipped flowers are borne in loose whorls in the leaf axils. The fruit splits into four small nutlets.[6]

Height: 30-70 (up to 150) cm
Habit: Erect, bushy perennial herb
Leaves: Opposite, ovate to heart-shaped, toothed, wrinkled, lemon-scented when crushed
Flowers: Small, pale yellow to white, two-lipped, in loose axillary whorls
Stem: Square, branched, hairy
Root: Fibrous, spreading perennial rootstock
Fruit: Four small nutlets (typical Lamiaceae schizocarp)
Flowering Period: June-August

Perennial herb, 30-90 cm tall, a sterile natural hybrid (Mentha aquatica x M. spicata) that spreads by rhizomes and surface stolons rather than viable seed. Stems are square, often purple-tinged. Leaves are opposite, lance-shaped to ovate with a sharply toothed margin, and release a strong menthol scent when crushed. Small, pale purple flowers are borne in dense, interrupted terminal spikes.[2]

Height: 30-90 cm
Habit: Rhizomatous, mat-forming perennial herb, sterile hybrid
Leaves: Opposite, lance-shaped to ovate, sharply toothed, strongly menthol-scented
Flowers: Small, pale purple, in dense interrupted terminal spikes
Stem: Square, often purple-tinged
Root: Spreading rhizomes and surface stolons
Fruit: Rarely sets seed (sterile hybrid); propagated vegetatively
Flowering Period: July-September

Habitat

Native to southern Europe, the Mediterranean and western Asia, widely cultivated and naturalised in gardens, hedgebanks and waste ground across temperate regions, favouring sunny to lightly shaded, well-drained soils.[6]

A cultivated hybrid grown worldwide as a crop and garden herb, propagated vegetatively since it rarely sets viable seed; naturalised in damp ground - streambanks, ditches and waste places - in temperate regions.[2]

Harvesting

Leaves and flowering tops are cut just before or at the start of flowering (summer), when the volatile-oil content is highest, and dried quickly at low temperature away from direct light, since the aromatic oil is heat- and light-sensitive.[6]

Parts: Leaf, Flowering tops
Season: Summer, just before or at flowering

Aerial parts are cut at or just before full flowering (mid- to late summer), when the essential-oil (menthol) content peaks, then dried quickly out of direct sun, or distilled fresh for essential oil.[3]

Parts: Leaf, Flowering tops
Season: Mid- to late summer, at or just before flowering

Harvest Readiness

[11]

Part: leaf
Signals: Gather the leaves from late spring to early autumn, ideally just before flowering for the best flavour and oil.
Basis: traditional
Source Quote: Leaves can be harvested from late spring to early autumn, ideally just before flowering for the best flavor.
Species Confirmed: 1
Notes: PFAF (REF-3292); the leaves are gathered just before flowering (late spring to early autumn), when the aromatic oil is best. Single lineage -> provisional.

[11]

Part: flower
Signals: Gather the flowering tops just before or as the plant comes into flower, in summer.
Basis: traditional
Source Quote: harvested just before or just after flowering
Species Confirmed: 1
Notes: PFAF (REF-3292); for drying, the plant is gathered just before or just after flowering (in flower June-October). Single lineage -> provisional.

[33]

Part: leaf
Signals: Cut the leaves as the plant comes into flower, when the aromatic oil peaks.
Basis: traditional
Source Quote: The leaves are harvested as the plant comes into flower and can be dried for later use.
Species Confirmed: 1
Notes: PFAF (REF-3293); the leaves are harvested as the plant comes into flower (in flower August-October). Single lineage -> provisional.

[33]

Part: flower
Signals: Gather the flowering tops as the plant comes into flower, in late summer to autumn.
Basis: traditional
Source Quote: The leaves are harvested as the plant comes into flower and can be dried for later use.
Species Confirmed: 1
Notes: PFAF (REF-3293); the flowering tops are gathered as the plant comes into flower. Single lineage -> provisional.

Traditional Uses

Lemon balm has a long European tradition as a calming, 'cheering' herb for nervous tension, poor sleep and mild anxiety, and as a carminative for indigestion, bloating and cramping; topically it has traditionally been applied to cold sores. Modern clinical trials support anxiolytic and mood-related benefits and antiviral activity against herpes simplex virus, consistent with these traditional uses.[4, 6, 9]

Peppermint has one of the best-documented traditional uses of any herb - as a carminative and antispasmodic for indigestion, bloating and colic. Enteric-coated peppermint oil capsules are among the most clinically validated herbal treatments for irritable bowel syndrome, and topical or inhaled peppermint oil is traditionally and clinically used for tension-type headache and muscular aches.[1, 2, 4, 5]

Preparations

Infusion (tea)[6]

Dried leaf steeped in hot water, the classic way of taking lemon balm for calming and digestive support.

Standardised extract capsule[1, 2]

Encapsulated dry extract, the form used in clinical trials studying lemon balm for anxiety and mood; follow product-specific dosing.

Topical cream[8]

Concentrated leaf extract cream applied to cold sores (herpes labialis) at the earliest sign of an outbreak.

Tincture[12]

Tincture of the dried leaf, 2-6 ml one to three times daily per the EU herbal monograph. Educational reference only, not a prescription.

Infusion (tea)[1]

Dried leaf steeped in hot water, the classic digestive tea.

Enteric-coated oil capsules[4, 34, 35, 36]

Standardised peppermint oil in enteric-coated capsules, the clinically studied form for irritable bowel syndrome, releasing the oil in the intestine rather than the stomach.

Essential oil (topical)[5]

Diluted essential oil applied to the temples and neck for tension-type headache.

Dosage

Infusion (tea)[12]

The EU herbal monograph gives 1.5-4.5 g of the comminuted leaf in 150 mL of boiling water as an infusion, 1-3 times daily, in adolescents over 12, adults and elderly; a liquid extract at 2-4 mL and a tincture at 2-6 mL, both 1-3 times daily, are also listed. If symptoms persist longer than 2 weeks a healthcare practitioner should be consulted. Not recommended under 12 years. Educational reference only, not a prescription.

Standardised extract[1, 2]

Clinical trials for anxiety and mood have used standardised dry-extract capsules; dosing varies by product concentration, so follow the manufacturer's guidance. Educational reference only, not a prescription.

Enteric-coated oil capsules[34, 35, 36]

Duke (2002) and Commission E guidance: about 0.6 mL enteric-coated oil two to three times daily between meals for IBS-type digestive complaints. Educational reference only, not a prescription.

Dried leaf infusion[34, 35, 36]

Traditional guidance: about 1.5-3 g dried leaf as a tea, up to three times daily for digestive complaints. Educational reference only, not a prescription.

References

REF-1193, REF-1194, REF-1195, REF-1196, REF-1197, REF-1198, REF-1199, REF-1200, REF-1201, REF-1202
REF-1203, REF-1204, REF-1205, REF-1206, REF-1207, REF-1208, REF-1209, REF-1210, REF-1211, REF-1212, REF-3037, REF-3038, REF-3039, REF-3040, REF-3041, REF-3042, REF-3043, REF-3044, REF-3045, REF-3046, REF-3047, REF-3048, REF-3049, REF-3050, REF-3051, REF-3052, REF-3053, REF-3054, REF-3055, REF-3056, REF-3057, REF-3058

Drug Class Interactions

Sedatives Cns Depressants[17, 18, 19]Caution
Mechanism: Lemon balm has calming, sedative effects (a randomised controlled trial found it reduces anxiety, stress and sleep disturbance); taken with sedatives, sleeping tablets or other central-nervous-system depressants (including alcohol) it may add to drowsiness and slowed reactions.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Not documented

Pairings

Passiflora Incarnata[18, 20]

Lemon balm and passionflower are both gentle, GABA-acting calming herbs often blended together in anti-anxiety and sleep formulas; combined use may deepen relaxation but also add to drowsiness.

Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Not documented

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

  1. Mathews, I.M., Eastwood, J., Lamport, D.J., Cozannet, R.L. and others (2024) 'Clinical Efficacy and Tolerability of Lemon Balm (Melissa officinalis L.) in Psychological Well-Being: A Review', Nutrients, 16(20), pp. 3545. doi:10.3390/nu16203545 Meta-analysis / review
    https://doi.org/10.3390/nu16203545
  2. Ghazizadeh, J., Sadigh-Eteghad, S., Marx, W., Fakhari, A. and others (2021) 'The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis', Phytotherapy Research, 35(12), pp. 6690-6705. doi:10.1002/ptr.7252 Meta-analysis / review
    https://doi.org/10.1002/ptr.7252
  3. Shahsavari, K., Shams Ardekani, M.R., Khanavi, M., Jamialahmadi, T. and others (2024) 'Effects of Melissa officinalis (lemon balm) consumption on serum lipid profile: a meta-analysis of randomized controlled trials', BMC Complementary Medicine and Therapies, 24(1), pp. 146. doi:10.1186/s12906-024-04442-0 Meta-analysis / review
    https://doi.org/10.1186/s12906-024-04442-0
  4. Petrisor, G., Motelica, L., Craciun, L.N., Oprea, O.C. and others (2022) 'Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems-A Review', International Journal of Molecular Sciences, 23(7), pp. 3591. doi:10.3390/ijms23073591 Meta-analysis / review
    https://doi.org/10.3390/ijms23073591
  5. Heshmati, J., Morvaridzadeh, M., Sepidarkish, M., Fazelian, S. and others (2020) 'Effects of Melissa officinalis (Lemon Balm) on cardio-metabolic outcomes: A systematic review and meta-analysis', Phytotherapy Research, 34(12), pp. 3113-3123. doi:10.1002/ptr.6744 Meta-analysis / review
    https://doi.org/10.1002/ptr.6744
  6. Shakeri, A., Sahebkar, A. and Javadi, B (2016) 'Melissa officinalis L. - A review of its traditional uses, phytochemistry and pharmacology', Journal of Ethnopharmacology, 188, pp. 204-228. doi:10.1016/j.jep.2016.05.010 Meta-analysis / review
    https://doi.org/10.1016/j.jep.2016.05.010
  7. Zam, W., Quispe, C., Sharifi-Rad, J., Lopez, M.D. and others (2022) 'An Updated Review on The Properties of Melissa officinalis L.: Not Exclusively Anti-anxiety', Frontiers in Bioscience (Scholar Edition), 14(2), pp. 16. doi:10.31083/j.fbs1402016 Meta-analysis / review
    https://doi.org/10.31083/j.fbs1402016
  8. Chang, J.Y., Balch, C., Puccio, J. and Oh, H.S (2023) 'A Narrative Review of Alternative Symptomatic Treatments for Herpes Simplex Virus', Viruses, 15(6), pp. 1314. doi:10.3390/v15061314 Meta-analysis / review
    https://doi.org/10.3390/v15061314
  9. Ulbricht, C., Brendler, T., Gruenwald, J., Kligler, B. and others (2005) 'Lemon balm (Melissa officinalis L.): an evidence-based systematic review by the Natural Standard Research Collaboration', Journal of Herbal Pharmacotherapy, 5(4), pp. 71-114. doi:10.1080/j157v05n04_08 Meta-analysis / review
    https://doi.org/10.1080/j157v05n04_08
  10. Stojanovic, N.M., Mladenovic, M.Z., Maslovaric, A., Stojiljkovic, N.I. and others (2021) 'Lemon balm (Melissa officinalis L.) essential oil and citronellal modulate anxiety-related symptoms - In vitro and in vivo studies', Journal of Ethnopharmacology, 284, pp. 114788. doi:10.1016/j.jep.2021.114788 Preclinical
    https://doi.org/10.1016/j.jep.2021.114788
  11. Plants For A Future 'Melissa officinalis (Lemon Balm)'. Available at: https://pfaf.org/user/Plant.aspx?LatinName=Melissa+officinalis Traditional / reference
    https://pfaf.org/user/Plant.aspx?LatinName=Melissa+officinalis
  12. European Medicines Agency (HMPC) (2013) 'Community herbal monograph on Melissa officinalis L., folium'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-melissa-officinalis-l-folium_en.pdf Traditional / reference
    https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-melissa-officinalis-l-folium_en.pdf
  13. Hoffmann, D (2003) 'Medical Herbalism'. Traditional / reference
    https://scholar.google.com/scholar?q=Medical%20Herbalism
  14. Kennedy, D.O. et al (2002) 'Modulation of mood and cognitive performance following acute administration of Melissa officinalis', 27(2), pp. 256--261. doi:10.1016/s0091-3057(02)00777-3 Randomized trial
    https://doi.org/10.1016/s0091-3057(02)00777-3
  15. Petersen, M. and Simmonds, M.S.J (2003) 'Rosmarinic acid', 62(2), pp. 121--125. Traditional / reference
    https://scholar.google.com/scholar?q=Rosmarinic%20acid
  16. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  17. Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
    https://doi.org/10.1002/ptr.8201
  18. Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
    https://doi.org/10.1177/1534735404265003
  19. Haybar, H., Javid, A.Z., Haghighizadeh, M.H., Valizadeh, E., Mohaghegh, S.M. and Mohammadzadeh, A (2018) 'The effects of Melissa officinalis supplementation on depression, anxiety, stress, and sleep disorder in patients with chronic stable angina', Clinical Nutrition ESPEN, 26, pp. 47-52. doi:10.1016/j.clnesp.2018.04.015 Randomized trial
    https://doi.org/10.1016/j.clnesp.2018.04.015
  20. Keck, M.E., Nicolussi, S., Spura, K., Blohm, C., Zahner, C. and Drewe, J (2020) 'Effect of the fixed combination of valerian, lemon balm, passionflower, and butterbur extracts (Ze 185) on the prescription pattern of benzodiazepines in hospitalized psychiatric patients', Phytotherapy Research, 34(6), pp. 1436-1445. doi:10.1002/ptr.6618 Clinical study
    https://doi.org/10.1002/ptr.6618
  1. McKay, D.L. and Blumberg, J.B (2006) 'A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.)', Phytotherapy Research, 20(8), pp. 619-633. doi:10.1002/ptr.1936 Meta-analysis / review
    https://doi.org/10.1002/ptr.1936
  2. Mahendran, G. and Rahman, L.U (2020) 'Ethnomedicinal, phytochemical and pharmacological updates on Peppermint (Mentha x piperita L.)-A review', Phytotherapy Research, 34(9), pp. 2088-2139. doi:10.1002/ptr.6664 Meta-analysis / review
    https://doi.org/10.1002/ptr.6664
  3. Zhao, H., Ren, S., Yang, H., Tang, S. and others (2022) 'Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application', Biomedicine & Pharmacotherapy, 154, pp. 113559. doi:10.1016/j.biopha.2022.113559 Meta-analysis / review
    https://doi.org/10.1016/j.biopha.2022.113559
  4. Keifer, D., Ulbricht, C., Abrams, T.R., Basch, E. and others (2007) 'Peppermint (Mentha piperita): an evidence-based systematic review by the Natural Standard Research Collaboration', Journal of Herbal Pharmacotherapy, 7(2), pp. 91-143. doi:10.1300/j157v07n02_07 Meta-analysis / review
    https://doi.org/10.1300/j157v07n02_07
  5. Gobel, H., Heinze, A., Heinze-Kuhn, K., Gobel, A. and Gobel, C (2016) 'Peppermint oil in the acute treatment of tension-type headache', Schmerz, 30(3), pp. 295-310. doi:10.1007/s00482-016-0109-6 Meta-analysis / review
    https://doi.org/10.1007/s00482-016-0109-6
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  25. Orhan, İ.E. and Kartal, M. and Kan, Y. and Şener, B (2008) 'Activity of Essential Oils and Individual Components against Acetyland Butyrylcholinesterase', Zeitschrift für Naturforschung C. doi:10.1515/znc-2008-7-813 Preclinical
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only - not medical advice. Always consult a qualified practitioner before using medicinal plants.