Guarana (Paullinia cupana Mart.) protects against amyloid-beta toxicity in Caenorhabditis elegans through heat shock protein response activation
Abstract
Chronic guarana (Paullinia cupana) ethanolic extract treatment decreased amyloid-beta aggregate formation in a Caenorhabditis elegans model of Alzheimer's disease, preventing behavioural deficits and oxidative damage through activation of the heat-shock-protein response, indicating neuroprotective potential against amyloidogenic neurodegeneration.
Referenced for these plants
How to cite
Zamberlan, D.C., Arantes, L.P., Machado, M.L., da Silveira, T.L. and others (2020) 'Guarana (Paullinia cupana Mart.) protects against amyloid-beta toxicity in Caenorhabditis elegans through heat shock protein response activation', Nutritional Neuroscience, 23(6), pp. 444-454. doi:10.1080/1028415X.2018.1517473
This reference is part of the evidence base for the Omnia Sana plant database. Source links open the original publication; Omnia Sana does not host third-party content.