Serenoa repens extract for benign prostate hyperplasia: a randomized controlled trial

Abstract

Objective To compare the effect of a Serenoa repens extract with placebo for symptoms of benign prostatic hyperplasia (BPH). Patients and methods In a double-blind placebo-controlled randomized trial between January 1999 and March 2000, 100 men with symptoms of BPH, aged Results There was no significant difference between the treatments over the 12 weeks of the study in the IPSS, peak urinary flow rate or for the IIEF questionnaire. Conclusions During the trial all participants had some improvement in their symptoms of BPH but there was no significant beneficial effect of this S. repens extract over placebo in this 12-week trial.