Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora
Preclinical
Abstract
Hot-water and ethanol extracts of Scutellaria lateriflora (mad-dog skullcap) bound to the serotonergic 5-HT7 receptor, an activity attributed at least in part to its flavonoids (scutellarin, ikonnikoside I), providing a mechanistic basis for its calming nervine use.
Referenced for these plants
How to cite
Gafner, S., Bergeron, C., Batcha, L.L., Reich, J. and others (2003) 'Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora', Journal of Natural Products, 66(4), pp. 535-537. doi:10.1021/np0205102
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