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Effect of valerian, valerian/hops extracts, and valerenic acid on glucuronidation in vitro

Alkharfy, K.M. and Frye, R.F. · Xenobiotica · 2007

Preclinical

Abstract

Valerian (Valeriana officinalis) and valerian/hops extracts and the constituent valerenic acid inhibited UDP-glucuronosyltransferase activity in vitro, suggesting that valerian-containing products may interfere with the glucuronidation of drugs - a relevant herb-drug-interaction consideration.

Referenced for these plants

How to cite

Alkharfy, K.M. and Frye, R.F (2007) 'Effect of valerian, valerian/hops extracts, and valerenic acid on glucuronidation in vitro', Xenobiotica, 37(2), pp. 113-123. doi:10.1080/00498250601050420

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