← Reference Library

Peppermint (Mentha piperita) extract effectively inhibits cytochrome P450 3A4 (CYP3A4) mRNA induction in rifampicin-treated HepG2 cells

Kobayashi, T., Sugaya, K., Onose, J. and Abe, N. · Bioscience, Biotechnology, and Biochemistry · 2019

Preclinical
View original source →

Abstract

Peppermint (Mentha piperita) extract and its constituent pheophorbide a suppressed rifampicin-induced CYP3A4 mRNA expression in HepG2 cells, characterising a potential herb-drug interaction mechanism relevant to the safe use of peppermint.

Referenced for these plants

Peppermintbalm mintbrandy mintMentha × piperita

How to cite

Kobayashi, T., Sugaya, K., Onose, J. and Abe, N (2019) 'Peppermint (Mentha piperita) extract effectively inhibits cytochrome P450 3A4 (CYP3A4) mRNA induction in rifampicin-treated HepG2 cells', Bioscience, Biotechnology, and Biochemistry, 83(7), pp. 1181-1192. doi:10.1080/09168451.2019.1608802

This reference is part of the evidence base for the Omnia Sana plant database. Source links open the original publication; Omnia Sana does not host third-party content.

Powered by
►
Necessary cookies enable essential site features like secure log-ins and consent preference adjustments. They do not store personal data.
None
►
Functional cookies support features like content sharing on social media, collecting feedback, and enabling third-party tools.
None
►
Analytical cookies track visitor interactions, providing insights on metrics like visitor count, bounce rate, and traffic sources.
None
►
Advertisement cookies deliver personalized ads based on your previous visits and analyze the effectiveness of ad campaigns.
None
Powered by