Plant Profile

Turkey tail

Trametes versicolor
Family: Polyporaceae  ·  Parts used: Mycelium, Whole Plant  ·  Also known as: Turkey tail mushroom, many-zoned polypore, yun zhi

The complete database record: 3 documented constituents, 6 pharmacological actions, 4 traditional / indicated uses, with 18 cited sources.

Botanical Description

Bracket fungus (not a true plant) forming thin, tough, fan-shaped, overlapping shelves on dead or decaying hardwood, with a velvety, concentrically zoned upper surface in bands of brown, tan, cream, blue-grey and rust, and a white, minutely pored underside.

Height: Individual brackets 2-8 cm across, forming overlapping clusters
Habit: Bracket (shelf) fungus growing directly from dead wood, in tiered, overlapping clusters
Leaves: Not applicable (fungus); the fruiting body is a thin, tough bracket
Flowers: Not applicable (fungus); reproduces via spores released from pores on the underside
Stem: No true stem; the bracket attaches directly to the wood
Root: Not applicable; mycelium threads through the wood substrate
Fruit: Fan-shaped fruiting body (bracket) with a white, densely pored underside
Flowering Period: Fruiting bodies present year-round, most abundant in autumn

Habitat & Distribution

Grows on dead, dying or fallen hardwood logs, stumps and branches in woodlands worldwide, including Europe, Asia and North America.

Harvesting

Fresh brackets are harvested by cutting from the wood; for medicinal use the tough fruiting body is typically dried and then decocted (simmered) for a long time, or extracted, since the beneficial polysaccharides are not well-extracted by simple infusion.

Parts: Mycelium, Whole Plant
Season: Year-round, most abundant in autumn

Key Constituents

Beta-glucan polysaccharides[12, 13]

The principal immunomodulating constituents, forming the basis of PSK/PSP extracts.

Polysaccharides
Polysaccharopeptide (PSK/PSP, protein-bound polysaccharide)[13]

Protein-bound polysaccharide complex studied extensively as an adjunct immunotherapy.

Polysaccharides
Phenolic compounds and triterpenes[14]

Minor antioxidant constituents.

Phenolic compoundsTerpenes / terpenoids

Pharmacological Actions

Anti-inflammatory[12, 13, 14]
Anticancer (preclinical)[1, 2, 3, 4, 5, 6, 9, 10, 12, 13, 14]
Antimicrobial[12, 13, 14]
Antioxidant[8, 9, 10, 12, 13, 14]
Antiviral[12, 13, 14]
Immunomodulator / immune support[1, 2, 3, 4, 5, 6, 7, 9, 12, 13, 14]

Traditional & Indicated Uses

Cancer (anticancer research)[1, 2, 3, 4, 6, 13]Strong · 9/10

inferred from anticancer action

Mechanistic Exclude Ids: REF-0300
Evidence: 9
Label: Cancer (anticancer research)

more plants for cancer (anticancer research) →detailed sources →

Cold & flu[12]Preliminary · 1/10

inferred from antiviral action

Mechanistic Exclude Ids: REF-0282, REF-0300, REF-1582, REF-1583, REF-1584, REF-1585, REF-1587, REF-1588
Evidence: 1
Label: Cold & flu

more plants for cold & flu →detailed sources →

Immune support[12, 13]Preliminary · 1/10
Mechanistic Exclude Ids: REF-0300
Evidence: 1
Label: Immune support

more plants for immune support →detailed sources →

Infection (general)[12]Preliminary · 1/10

inferred from antimicrobial action

Mechanistic Exclude Ids: REF-0282, REF-0300
Evidence: 1
Label: Infection (general)

more plants for infection (general) →detailed sources →

Traditional Use & History

Turkey tail has a long history of use in traditional Chinese medicine (as yun zhi) and is one of the most researched medicinal mushrooms, with standardized polysaccharide-K (PSK) and polysaccharopeptide (PSP) extracts used clinically in Japan and China alongside conventional cancer treatment to support immune function.[12, 13, 14]

Preparations

Long decoction[12]

Dried fruiting body simmered in water for an extended period (often 1-2 hours) to extract the beta-glucan polysaccharides, then strained.

Standardized extract (PSK/PSP)[13]

Standardized polysaccharide-K (PSK) or polysaccharopeptide (PSP) extract, the pharmaceutical-grade forms used in clinical research.

Dosage

Standardized extract[13]

Clinical research on PSK commonly uses around 3 g daily in divided doses. Educational reference only, not a prescription.

Safety, Cautions & Contraindications

Safety note[12, 13, 14]Caution

Generally very safe and well tolerated. Rare cases of digestive upset or allergic reaction. No significant known drug interactions at normal doses. The PSK pharmaceutical form is used safely alongside standard cancer treatments. Suitable for most adults.

Safety note[12, 13, 14, 15]Info

Duke (2002) does not include a dedicated entry for Turkey tail mushroom (Trametes versicolor) in the Handbook of Medicinal Herbs, Second Edition.

Dangerous Lookalikes

Stereum Hirsutum[16, 17, 18]Caution
Confused Part: The whole fan-shaped bracket (the concentrically zoned shelf growing on dead hardwood), especially the top surface, which looks almost identical from above.
Confusion Context: False turkey tail (Stereum hirsutum, and the near-identical Stereum ostrea) is the commonest fungus mistaken for medicinal turkey tail. Seen from above the two are near-identical: overlapping, fan-shaped, concentrically banded, fuzzy-topped brackets on dead wood. Stereum is NOT poisonous - it is simply inedible (too thin and leathery) and there are no documented poisonings. The problem is that it is a crust fungus lacking the medicinal polysaccharides of true turkey tail, so anyone who brews it gets a worthless tea. This record exists to prevent a wasted, ineffective harvest, not to warn of poisoning.
Distinguishing Features: UNDERSIDE (decisive): true turkey tail has a whitish PORE surface underneath, densely covered with tiny pores/tubes (about 2-5 per mm, visible with a hand lens). False turkey tail (Stereum) has a completely SMOOTH, poreless underside - it is a crust fungus, not a polypore., Underside colour: true turkey tail's pore surface is white to off-white. Stereum's smooth underside is typically tan, yellowish, greyish or pale reddish-brown; a coloured, non-white underside is a red flag., Texture: true turkey tail is thin and flexible; Stereum tends to be tougher, more leathery and often wavier at the margin.
Key Test: Turn the bracket over and look at the underside with a hand lens. Genuine turkey tail shows a white surface densely covered in tiny pores (roughly 2-5 per mm). If the underside is SMOOTH and poreless (and often tan/orange/brown rather than white), it is false turkey tail (Stereum) - discard it. Smooth underside = not turkey tail.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Harvest Readiness

[11]

Part: fruiting-body
Signals: Harvest the fresh, pliable brackets - flexible flesh with a white growing edge, colour fully developed - before they toughen, dry and fade with age (most abundant in autumn).
Basis: traditional
Source Quote: Turkey tails may persist on wood for 2-3 years, but when the mushroom is fresh it will have white spores and flexible flesh.
Species Confirmed: 1
Notes: Eat The Planet (REF-3354) for Trametes versicolor; harvest the fresh brackets - flexible flesh and a white growing edge - before they toughen and fade. Single source -> provisional. SAFETY: the inedible false turkey tail (Stereum hirsutum) is a lookalike - true turkey tail has visible pores on the underside, Stereum has a smooth underside; see Dangerous Lookalikes.

External Identifiers

References & Sources

  1. Pilkington, K., Wieland, L.S., Teng, L., Jin, X.Y. and others (2022) 'Coriolus (Trametes) versicolor mushroom to reduce adverse effects from chemotherapy or radiotherapy in people with colorectal cancer', Cochrane Database of Systematic Reviews, 11(11), pp. CD012053. doi:10.1002/14651858.CD012053.pub2 Meta-analysis / review
    https://doi.org/10.1002/14651858.CD012053.pub2
  2. Habtemariam, S (2020) 'Trametes versicolor (Synn. Coriolus versicolor) Polysaccharides in Cancer Therapy: Targets and Efficacy', Biomedicines, 8(5), pp. 135. doi:10.3390/biomedicines8050135 Meta-analysis / review
    https://doi.org/10.3390/biomedicines8050135
  3. Fritz, H., Kennedy, D.A., Ishii, M., Fergusson, D. and others (2015) 'Polysaccharide K and Coriolus versicolor extracts for lung cancer: a systematic review', Integrative Cancer Therapies, 14(3), pp. 201-211. doi:10.1177/1534735415572883 Meta-analysis / review
    https://doi.org/10.1177/1534735415572883
  4. Tsang, K.W., Lam, C.L., Yan, C., Mak, J.C. and others (2003) 'Coriolus versicolor polysaccharide peptide slows progression of advanced non-small cell lung cancer', Respiratory Medicine, 97(6), pp. 618-624. doi:10.1053/rmed.2003.1490 Randomized trial
    https://doi.org/10.1053/rmed.2003.1490
  5. Ng, T.B (1998) 'A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom Coriolus versicolor (Basidiomycetes: Polyporaceae)', General Pharmacology, 30(1), pp. 1-4. doi:10.1016/s0306-3623(97)00076-1 Meta-analysis / review
    https://doi.org/10.1016/s0306-3623(97)00076-1
  6. Kowalczewska, M., Piotrowski, J., Jedrzejewski, T. and Kozak, W (2016) 'Polysaccharide peptides from Coriolus versicolor exert differential immunomodulatory effects on blood lymphocytes and breast cancer cell line MCF-7 in vitro', Immunology Letters, 174, pp. 37-44. doi:10.1016/j.imlet.2016.04.010 Preclinical
    https://doi.org/10.1016/j.imlet.2016.04.010
  7. Jedrzejewski, T., Piotrowski, J., Kowalczewska, M., Wrotek, S. and Kozak, W (2015) 'Polysaccharide peptide from Coriolus versicolor induces interleukin 6-related extension of endotoxin fever in rats', International Journal of Hyperthermia, 31(6), pp. 626-634. doi:10.3109/02656736.2015.1046953 Preclinical
    https://doi.org/10.3109/02656736.2015.1046953
  8. Scarpari, M., Reverberi, M., Parroni, A., Scala, V. and others (2017) 'Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects', PLoS One, 12(8), pp. e0171412. doi:10.1371/journal.pone.0171412 Preclinical
    https://doi.org/10.1371/journal.pone.0171412
  9. Lysakowska, P., Sobota, A. and Wirkijowska, A (2023) 'Medicinal Mushrooms: Their Bioactive Components, Nutritional Value and Application in Functional Food Production - A Review', Molecules, 28(14), pp. 5393. doi:10.3390/molecules28145393 Meta-analysis / review
    https://doi.org/10.3390/molecules28145393
  10. Wang, K.F., Sui, K.Y., Guo, C. and Liu, C.Z (2017) 'Quorum sensing molecule-farnesol increased the production and biological activities of extracellular polysaccharide from Trametes versicolor', International Journal of Biological Macromolecules, 104(Pt A), pp. 377-383. doi:10.1016/j.ijbiomac.2017.06.053 Preclinical
    https://doi.org/10.1016/j.ijbiomac.2017.06.053
  11. Eat The Planet 'Trametes versicolor - Turkey Tail'. Available at: https://eattheplanet.org/trametes-versicolor-turkey-tail/ Traditional / reference
    https://eattheplanet.org/trametes-versicolor-turkey-tail/
  12. Chu, K.K., Ho, S.S. and Chow, A.H (2002) 'Coriolus versicolor: a medicinal mushroom with promising immunotherapeutic values', 42(9), pp. 976--984. doi:10.1177/0091270002042009004 Traditional / reference
    https://doi.org/10.1177/0091270002042009004
  13. Standish, L.J., Wenner, C.A., Sweet, E.S., Bridge, C., Nelson, A., Martzen, M., Novack, J. and Torkelson, C (2008) 'Trametes versicolor mushroom immune therapy in breast cancer', 6(3), pp. 122--128. Traditional / reference
    https://scholar.google.com/scholar?q=Trametes%20versicolor%20mushroom%20immune%20therapy%20in%20breast%20cancer
  14. Wasser, S.P (2011) 'Current findings, future trends, and unsolved problems in studies of medicinal mushrooms', 89(5), pp. 1323--1332. doi:10.1007/s00253-010-3067-4 Randomized trial
    https://doi.org/10.1007/s00253-010-3067-4
  15. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  16. Macalester College, Katharine Ordway Natural History Study Area 'Turkey Tail Fungus (Trametes versicolor)'. Available at: https://www.macalester.edu/ordway/biodiversity/inventory/turkeytailfungus/ Traditional / reference
    https://www.macalester.edu/ordway/biodiversity/inventory/turkeytailfungus/
  17. Missouri Department of Conservation 'False Turkey Tail (Stereum ostrea)'. Available at: https://mdc.mo.gov/discover-nature/field-guide/false-turkey-tail Traditional / reference
    https://mdc.mo.gov/discover-nature/field-guide/false-turkey-tail
  18. Kuo, Michael 'Stereum ostrea (False Turkey Tail)'. Available at: https://www.mushroomexpert.com/stereum_ostrea.html Traditional / reference
    https://www.mushroomexpert.com/stereum_ostrea.html

This fact sheet is generated automatically from the Omnia Sana plant database and reflects its latest synced data. It is provided for educational purposes only and is not medical advice. How this site is built.

Selected studies & references

Educational use only. This profile summarises traditional and scientific sources for reference. It is not medical advice and not a substitute for a qualified practitioner. Some plants carry safety cautions and drug interactions - always check before use.
This profile is assembled automatically from the Omnia Sana plant database, which we curate by hand. How this site is built.
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