Journal

Horse Chestnut

July 2, 2026 · Omnia Sana
Aesculus hippocastanum
Family: Sapindaceae  ·  Parts used: Seed (standardised extract)  ·  Also known as: Conker tree, Buckeye

Key actions

Anti-inflammatoryAnti-oedematous (reduces swelling)Venotonic / vasoprotective

Traditional & clinical uses, by strength of evidence

  • Pain (general)Good
  • Swelling / fluid retentionGood
  • Varicose veinsGood
  • Arthritis / joint painTraditional
  • HaemorrhoidsTraditional
  • Inflammation (general)Traditional
  • Skin irritationTraditional

Selected studies & references

ReviewPhytochemical, ethnomedicinal and pharmacological applications of escin from Aesculus hippocastanum L. towards future medicine (2020)
ReviewHorse chestnut seed extract for chronic venous insufficiency (2012)
ReviewHorse chestnut seed extract for chronic venous insufficiency (2006)
PreclinicalVenoactive drugs in the management of chronic venous disease: A critical appraisal of the evidence and comparison with international guidelines (2026)
PreclinicalThe role of venoactive compounds in the treatment of chronic venous disease (2025)
PreclinicalAesculus hippocastanum extract and the main bioactive constituent beta-escin as antivirals agents against coronaviruses, including SARS-CoV-2 (2024)
PreclinicalPhytochemical Estimation and Therapeutic Amelioration of Aesculus hippocastanum L. Seeds Ethanolic Extract in Gastric Ulcer in Rats Possibly by Inhibiting Prostaglandin Synthesis (2023)
PreclinicalAnalysis of the Anti-Inflammatory and Anti-Osteoarthritic Potential of Flonat Fast, a Combination of Plant Extracts, Bromelain and Escin (Aesculus hippocastanum), Evaluated in In Vitro Models of Inflammation Relevant to Osteoarthritis (2022)

All 14 studies in the Knowledge Finder →

Educational use only. This profile summarises traditional and scientific sources for reference. It is not medical advice and not a substitute for a qualified practitioner. Some plants carry safety cautions and drug interactions — always check before use.

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