Plant Profile

Arnica

Arnica montana
Family: Asteraceae  ·  Parts used: Flower head (topical preparations)  ·  Also known as: Mountain arnica, Leopard's bane, Wolf's bane, Mountain tobacco

The complete database record: 4 documented constituents, 6 pharmacological actions, 12 traditional / indicated uses, with 19 cited sources.

Botanical Description

Aromatic mountain perennial herb with a basal rosette of oval, hairy leaves and one or two pairs of smaller opposite leaves on an erect, softly hairy flowering stem. Each stem bears one or a few large, bright golden-yellow, daisy-like flower heads with narrow, slightly twisted ray florets.[4]

Height: 20-60 cm
Habit: Erect, aromatic mountain perennial herb
Leaves: Basal rosette of oval, hairy leaves; one or two pairs of smaller opposite stem leaves
Flowers: Large, bright golden-yellow, daisy-like flower heads with narrow, slightly twisted ray florets
Stem: Erect, softly hairy, sparsely leaved flowering stem
Root: Short, blackish rhizome with fibrous roots
Fruit: Small, hairy achene with a pappus
Flowering Period: June-August

Habitat & Distribution

Grows in acidic, nutrient-poor mountain meadows, pastures and open woodland, typically at moderate to high elevations across central and northern Europe; increasingly scarce in the wild due to habitat loss and overharvesting.[4]

Harvesting

The flower heads are picked by hand as they open, in mid- to late summer, and dried quickly in a warm, shaded, airy place; wild populations are protected in many regions, so cultivated or sustainably wildcrafted material is preferred.[4]

Parts: Flower head (topical preparations)
Season: Mid- to late summer, as flowers open

Key Constituents

Sesquiterpene lactones (helenalin, dihydrohelenalin)[4]

The main anti-inflammatory principles; also responsible for the plant's toxicity and contact-allergy potential.

Sesquiterpene lactonesSesquiterpenes
Flavonoids[4]

Antioxidant and anti-inflammatory constituents.

Flavonoids
Essential oil, phenolic acids and coumarins[4]

Aromatic and supporting constituents of the flower.

Phenolic acidsEssential (volatile) oilCoumarins
Pyrrolizidine alkaloids (trace)[4]

Present in small amounts; relevant to the caution against internal use.

Alkaloids

Pharmacological Actions

Analgesic (pain relief)[4, 5, 16]

Topical analgesic for muscle soreness and pain

Anti-inflammatory[2, 4, 5, 6, 7, 8, 12, 16]

Topical anti-inflammatory for bruising, swelling and sprains

Anticancer (preclinical)[11, 17, 18]

Helenalin, the sesquiterpene lactone of Arnica montana, shows anticancer activity against multiple tumour types in vitro and in vivo, largely by covalently inhibiting NF-kappaB p65 and inducing apoptosis (preclinical).

Antimicrobial[4, 11]

Antimicrobial and antioxidant (in vitro)

Antioxidant[4, 11, 13]

Antimicrobial and antioxidant (in vitro)

Vulnerary (wound healing)[4, 9, 10]

Antiecchymotic / vulnerary (helps disperse bruises)

Traditional & Indicated Uses

Arthritis / joint pain[4, 16]Good · 7/10

inferred from anti-inflammatory action

Evidence: 7
Label: Arthritis / joint pain

more plants for arthritis / joint pain →detailed sources →

Back pain[4, 16]Good · 7/10

inferred from analgesic action

Evidence: 7
Label: Back pain

more plants for back pain →detailed sources →

Bruising[4, 16]Good · 7/10

Antiecchymotic / vulnerary (helps disperse bruises); Topical anti-inflammatory for bruising, swelling and sprains

Evidence: 7
Label: Bruising

more plants for bruising →detailed sources →

Cancer (anticancer research)[11, 17, 18]Preliminary · 2/10

Arnica montana and its constituent helenalin exert anticancer activity against several tumour types in vitro and in vivo, inhibiting NF-kappaB (p65) signalling, inducing apoptosis and synergizing with other anticancer agents (preclinical).

Evidence: 2
Label: Cancer (anticancer research)

more plants for cancer (anticancer research) →detailed sources →

Headache[4, 16]Good · 7/10

inferred from analgesic action

Evidence: 7
Label: Headache

more plants for headache →detailed sources →

Infection (general)[4]Preliminary · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)

more plants for infection (general) →detailed sources →

Inflammation (general)[4, 16]Good · 7/10

inferred from anti-inflammatory action

Evidence: 7
Label: Inflammation (general)

more plants for inflammation (general) →detailed sources →

Muscle soreness[4, 16]Good · 7/10

Topical analgesic for muscle soreness and pain

Evidence: 7
Label: Muscle soreness

more plants for muscle soreness →detailed sources →

Pain (general)[4, 16]Good · 7/10

Topical analgesic for muscle soreness and pain

Evidence: 7
Label: Pain (general)

more plants for pain (general) →detailed sources →

Skin irritation[4, 16]Good · 7/10

inferred from anti-inflammatory action

Evidence: 7
Label: Skin irritation

more plants for skin irritation →detailed sources →

Swelling / fluid retention[4, 16]Good · 7/10

Topical anti-inflammatory for bruising, swelling and sprains

Evidence: 7
Label: Swelling / fluid retention

more plants for swelling / fluid retention →detailed sources →

Wounds[4]Preliminary · 1/10

inferred from vulnerary action

Evidence: 1
Label: Wounds

more plants for wounds →detailed sources →

Traditional Use & History

Arnica flower has a long central European folk reputation, reflected in the name 'leopard's bane' and 'mountain tobacco', as a topical remedy for bruising, sprains, muscle soreness and swelling after minor injury, applied only to unbroken skin. Internal use of the whole herb has always been considered dangerous and is confined to highly diluted homeopathic preparations.[4]

Preparations

Topical cream/gel/ointment[4]

Standardised flower extract formulated into a cream, gel or ointment for external application to bruises, sprains and muscle soreness on unbroken skin.

Diluted tincture (topical)[4]

Alcoholic tincture of the dried flower heads, diluted before topical application as a compress; never taken internally in this form.

Dosage

Topical cream/gel[15]

The EU herbal monograph gives cutaneous use only, in adolescents, adults and elderly - a semi-solid preparation containing 20-25% tincture applied as a thin layer 2-3 times daily, a 50% liquid-extract preparation 2-4 times daily, or 2.5 mL of a liquid preparation as an impregnated dressing 3-4 times daily. Apply to unbroken skin only. If symptoms persist after 3 to 4 days a healthcare practitioner should be consulted. Not recommended under 12 years. Never taken by mouth except as a highly diluted homeopathic preparation. Educational reference only, not a prescription.

Safety, Cautions & Contraindications

Safety note[4, 19]Info

EXTERNAL USE ONLY on unbroken skin. Arnica is toxic if swallowed and can cause stomach pain, vomiting, diarrhoea, breathing difficulty, irregular heartbeat and, in serious cases, cardiac arrest; the only safe oral form is the highly diluted homeopathic preparation.

Safety note[19]Caution

Do not apply to broken or damaged skin, open wounds, eyes or mucous membranes.

Safety note[4]Info

As a member of the daisy family (Asteraceae) it can cause allergic contact dermatitis; prolonged topical use can also irritate the skin.

Safety note[16, 19]Caution

Avoid medicinal use during pregnancy and breastfeeding.

Harvest Readiness

[14]

Part: flower
Signals: Pick the flower heads when they are fully open, and dry promptly; the receptacles are sometimes removed as they are prone to insect attack.
Basis: traditional
Source Quote: The flowers are harvested when fully open and dried - the receptacles are sometimes removed since these are liable to be attacked by insects.
Species Confirmed: 1
Notes: Useful Temperate Plants (REF-3207) for Arnica montana. Single source -> provisional.

External Identifiers

References & Sources

  1. Toma, C.C., Marrelli, M., Puticiu, M., Conforti, F. and Statti, G (2024) 'Effects of Arnica montana Phytotherapeutic and Homeopathic Formulations on Traumatic Injuries and Inflammatory Conditions: A Systematic Review', Plants (Basel), 13(21), pp. 3112. doi:10.3390/plants13213112 Meta-analysis / review
    https://doi.org/10.3390/plants13213112
  2. Schmidt, T.J (2023) 'Arnica montana L.: Doesn't Origin Matter?', Plants (Basel), 12(20), pp. 3532. doi:10.3390/plants12203532 Traditional / reference
    https://doi.org/10.3390/plants12203532
  3. Dragos, D., Gilca, M., Gaman, L., Vlad, A., Iosif, L. et al (2017) 'Phytomedicine in Joint Disorders', Nutrients, 9(1), pp. 70. doi:10.3390/nu9010070 Traditional / reference
    https://doi.org/10.3390/nu9010070
  4. Kriplani, P., Guarve, K. and Baghael, U.S (2017) 'Arnica montana L. - a plant of healing: review', Journal of Pharmacy and Pharmacology, pp. 12724. doi:10.1111/jphp.12724 Traditional / reference
    https://doi.org/10.1111/jphp.12724
  5. Iannitti, T., Morales-Medina, J.C., Bellavite, P., Rottigni, V. and Palmieri, B (2016) 'Effectiveness and safety of Arnica montana in post-surgical setting, pain and inflammation', American Journal of Therapeutics, 23(1), pp. e184-e197. doi:10.1097/MJT.0000000000000036 Meta-analysis / review
    https://doi.org/10.1097/MJT.0000000000000036
  6. Verre, J., Boisson, M., Paumier, A., Tribolo, S. and Boujedaini, N (2023) 'Anti-inflammatory effects of Arnica montana (mother tincture and homeopathic dilutions) in various cell models', Journal of Ethnopharmacology, 318(Pt B), pp. 117064. doi:10.1016/j.jep.2023.117064 Preclinical
    https://doi.org/10.1016/j.jep.2023.117064
  7. Rohrl, J., Pique-Borras, M., Jaklin, M., Werner, M., Werz, O., Josef, H., Holz, H., Ammendola, A. and Kunstle, G (2023) 'Anti-inflammatory activities of Arnica montana planta tota versus flower extracts: analytical, in vitro and in vivo mouse paw oedema model studies', Plants, 12(6), pp. 1348. doi:10.3390/plants12061348 Preclinical
    https://doi.org/10.3390/plants12061348
  8. da Silva Prade, J., Balsamo, E.C., Machado, F.R., Poetini, M.R., Bortolotto, V.C., Araujo, S.M., Londero, L., Boeira, S.P., Sehn, C.P., de Gomes, M.G., Prigol, M. and Cattelan Souza, L (2020) 'Anti-inflammatory effect of Arnica montana in a UVB radiation-induced skin-burn model in mice', Cutaneous and Ocular Toxicology, 39(2), pp. 126-133. doi:10.1080/15569527.2020.1743998 Preclinical
    https://doi.org/10.1080/15569527.2020.1743998
  9. Zacarias, C.A., de Mendonca Florenziano, R.F., de Andrade, T.A.M., de Aro, A.A., do Amaral, M.E.C., Dos Santos, G.M.T. and Esquisatto, M.A.M (2023) 'Arnica montana L. associated with microcurrent accelerates the dermis reorganisation of skin lesions', International Journal of Experimental Pathology, 104(2), pp. 81-95. doi:10.1111/iep.12469 Preclinical
    https://doi.org/10.1111/iep.12469
  10. Chaiet, S.R. and Marcus, B.C (2016) 'Perioperative Arnica montana for reduction of ecchymosis in rhinoplasty surgery', Annals of Plastic Surgery, 76(5), pp. 477-482. doi:10.1097/SAP.0000000000000312 Randomized trial
    https://doi.org/10.1097/SAP.0000000000000312
  11. Zitek, T., Postruznik, V., Knez, Z., Golle, A., Daris, B. and Knez Marevci, M (2022) 'Arnica montana L. supercritical extraction optimization for antibiotic and anticancer activity', Frontiers in Bioengineering and Biotechnology, 10, pp. 897185. doi:10.3389/fbioe.2022.897185 Preclinical
    https://doi.org/10.3389/fbioe.2022.897185
  12. Sutovska, M., Capek, P., Kocmalova, M., Pawlaczyk, I., Zaczynska, E., Czarny, A., Uhliarikova, I., Gancarz, R. and Franova, S (2014) 'Characterization and pharmacodynamic properties of Arnica montana complex', International Journal of Biological Macromolecules, 69, pp. 214-221. doi:10.1016/j.ijbiomac.2014.05.051 Preclinical
    https://doi.org/10.1016/j.ijbiomac.2014.05.051
  13. Merfort, I. and Wendisch, D (1987) 'Flavonoid glycosides from Arnica montana and Arnica chamissonis', Planta Medica, 53(5), pp. 434-437. doi:10.1055/s-2006-962766 Preclinical
    https://doi.org/10.1055/s-2006-962766
  14. Fern, Ken 'Arnica montana — Useful Temperate Plants'. Available at: https://temperate.theferns.info/plant/Arnica+montana Traditional / reference
    https://temperate.theferns.info/plant/Arnica+montana
  15. European Medicines Agency (HMPC) (2012) 'Community herbal monograph on Arnica montana L., flos'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-arnica-montana-l-flos_en.pdf Traditional / reference
    https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-arnica-montana-l-flos_en.pdf
  16. Gaertner, K., Baumgartner, S. and Walach, H (2021) 'Is Homeopathic Arnica Effective for Postoperative Recovery? A Meta-analysis of Placebo-Controlled and Active Comparator Trials', Frontiers in Surgery. doi:10.3389/fsurg.2021.680930 Meta-analysis / review
    https://doi.org/10.3389/fsurg.2021.680930
  17. Kriplani, P. and Guarve, K (2020) 'Recent Patents on Anti-Cancer Potential of Helenalin', Recent Patents on Anti-Cancer Drug Discovery, 15(2), pp. 132-142. doi:10.2174/1574892815666200702142601 Preclinical
    https://doi.org/10.2174/1574892815666200702142601
  18. Drogosz, J. and Janecka, A (2019) 'Helenalin - A Sesquiterpene Lactone with Multidirectional Activity', Current Drug Targets, 20(4), pp. 444-452. doi:10.2174/1389450119666181012125230 Preclinical
    https://doi.org/10.2174/1389450119666181012125230
  19. National Capital Poison Center (Poison Control) (n.d.) 'Caution when using Arnica products'. Available at: https://www.poison.org/articles/caution-when-using-arnica-products-193 Traditional / reference
    https://www.poison.org/articles/caution-when-using-arnica-products-193

This fact sheet is generated automatically from the Omnia Sana plant database and reflects its latest synced data. It is provided for educational purposes only and is not medical advice. How this site is built.

Selected studies & references

Educational use only. This profile summarises traditional and scientific sources for reference. It is not medical advice and not a substitute for a qualified practitioner. Some plants carry safety cautions and drug interactions - always check before use.
This profile is assembled automatically from the Omnia Sana plant database, which we curate by hand. How this site is built.
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