Symptom → Plant Sources
Common coltsfoot (Tussilago farfara) as a tool for helping with Skin irritation
inferred from anti-inflammatory action
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Full Common coltsfoot monograph →All plants for skin irritation →
3 sources supporting Common coltsfoot for Skin irritation. Includes scientific publications, books, monographs and traditional-use references.
Mechanistic basis
This use is associated with the plant's anti-inflammatory action. Further evidence for that pharmacology:
Tussilago farfara (coltsfoot) is a widely used medicinal plant traditionally used for respiratory, digestive and circulatory ailments. Its alkaloids, flavonoids and terpenoids contribute to neuroprotective, anti-inflammatory, antioxidant and anticancer activities. This review covers extraction methods, phytochemistry, nanoparticle synthesis, ethnobotany, pharmacology and toxicology (pyrrolizidine-alkaloid safety considerations).
Tussilago farfara (coltsfoot, Kuan Dong Hua) has long been used to treat respiratory disorders and consumed as a vegetable. This review summarises its ethnobotanical value, phytochemistry (sesquiterpenoids, triterpenoids, flavonoids, pyrrolizidine alkaloids), pharmacology (anti-inflammatory, antioxidant, antitussive, neuroprotective), toxicity and quality control.
A new oplopane-type sesquiterpenoid (tussilagofarin) and a new chromone, together with 18 known compounds, were isolated from the flower buds of Tussilago farfara. Several sesquiterpenoids significantly inhibited LPS-induced nitric oxide production in RAW 264.7 macrophages, demonstrating the anti-inflammatory activity of coltsfoot constituents.