Symptom → Plant Sources

Perforate St John’s-wort (Hypericum perforatum) as a tool for helping with Skin irritation

Evidence

inferred from anti-inflammatory action

← Back to Symptom-to-Plant Lookup

Full Perforate St John’s-wort monograph →All plants for skin irritation →

Hypericum perforatum (St

Natural Standard · 2013

Traditional / referencePerforate St John’s-wortSt John's wortcommon St John's wortperforate St John's wortHypericum perforatum

Find this paper

St John

Linde, K. et al · 2008

Traditional / referencePerforate St John’s-wortSt John's wortcommon St John's wortperforate St John's wortHypericum perforatum

Find this paper

2 sources supporting Perforate St John’s-wort for Skin irritation. Includes scientific publications, books, monographs and traditional-use references.

Mechanistic basis

This use is associated with the plant's anti-inflammatory, emollient / skin-soothing actions. Further evidence for that pharmacology:

Hypericum perforatum L. attenuates depression by regulating Akkermansia muciniphila, tryptophan metabolism and NFkB-NLRP2-Caspase1-IL1beta pathway

Jiang, Z., Wang, F., Zhao, Y., Lu, L., Jiang, X., Huang, T., Lin, Y., Guo, L., Weng, Z. and Liu, E. · Phytomedicine · 2024

PreclinicalPerforate St John’s-wortSt John's wortcommon St John's wortperforate St John's wortHypericum perforatum

View source