Symptom → Plant Sources
Parsley (Petroselinum crispum) as a tool for helping with Liver support
inferred from hepatoprotective action
Petroselinum crispum (Mill.) Fuss (parsley) is a popular medicinal plant widely used in different traditional medicines all over the world. This paper provides an updated review on the traditional use, phytochemistry, and pharmacological activities of parsley. Parsley contains volatile compounds such as terpenes and terpenoids in the essential oil, as well as phenolic compounds in the plant extract. Parsley is traditionally used as a diuretic, liver and stomach tonic, and for urolithiasis and indigestion. Pharmacological investigations also confirm several biological activities of parsley including hepatoprotective, nephroprotective, antiurolithiatic, neuroprotective, cardioprotective, and antineoplastic effects in animal and cell-based studies. Parsley has currently demonstrated several pharmacological activities in preclinical studies; however, there is a big lack in clinical evidence. Considering parsley as a possible valuable medicinal food, future clinical trials are recommended to evaluate the clinical efficacy and safety of the plant in different health conditions.
Parsley (Petroselinum crispum) extract protected against bile-duct-ligation-induced liver injury in rats, reducing oxidative stress and fibrosis, demonstrating a hepatoprotective, antioxidant effect.
WHO estimates, around 80% of the especially developing world is indigent on complementary and alternative medicines which are prodigiously derived from herbal material. Parsley (Petroselinum crispum) is an important culinary herb originated from the Mediterranean region. It possesses small and dark seeds with volatile oil content. Petroselinum crispum is now planted throughout the world due to its usage in food industry, perfume manufacturing, soaps, and creams. Its main constituents subsume coumarins, furanocoumarins (bergapten, imperatori), ascorbic acid, carotenoids, flavonoids, apiole, various terpenoic compounds, phenyl propanoids, phathalides, and tocopherol. Due to these constituents, it has been annunciated to possess a number of possible medicinal emblematics including, antimicrobial, antianemic, menorrhagic, anticoagulant, antihyperlipidemic, antihepatotoxic, antihypertensive, diuretic effects, hypoglycaemic, hypouricemic, anti oxidative and estrogenic activities. In Morocco, Parsley is mostly used as an elixir to treat arterial hypertension, diabetes, cardiac and renal diseases. Antioxidant and antibacterial activities of parsley, made it propitious in food systems. Its ELI17 gene has been corroborated as a particularly fast-responding gene. There is a requisite for extensive research to avail the maximal benefits of this significant medicinal plant. The aim of this review paper is to divulge the chemical constituents of parsley that are explicitly related to substantial medicinal facets.
3 sources supporting Parsley for Liver support. Includes scientific publications, books, monographs and traditional-use references.
Mechanistic basis
This use is associated with the plant's hepatoprotective (liver support) action. Further evidence for that pharmacology:
Parsley (Petroselinum crispum) extract protected the liver of streptozotocin-induced diabetic rats, reducing oxidative stress and improving liver markers comparably to glibornuride, demonstrating antioxidant and hepatoprotective effects.
Parsley (Petroselinum crispum) extract attenuated hepatic steatosis in rats fed a fructose-enriched diet, reducing liver fat and oxidative stress, demonstrating a hepatoprotective effect.