Omnia SanaSymptom → Plant Sources
Pot marigold (Calendula officinalis) and Infection (general): evidence and sources
inferred from antifungal action
For educational purposes only, not medical advice. Always consult a qualified practitioner before using medicinal plants, especially alongside prescribed medication, during pregnancy, or for a serious condition.
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2 sources supporting Pot marigold for Infection (general). Includes scientific publications, books, monographs and traditional-use references.
Mechanistic basis
This use is associated with the plant's antifungal, antimicrobial actions. Further evidence for that pharmacology:
A new phytoconstituent; (6Z,9Z)-heptadeca-6,9-diene-5,11-dione ( 1 ) was isolated from Calendula officinalis methanol extract. The structure of 1 was determined based on the analysis of NMR spectra and HRESIMS. It was tested for antimicrobial and antiprotozoal activities. Compound 1 showed leishmanicidal activity against L. donovani amastigote with an IC 50 of 16.4394 µM and IC 90 of 28.9015 µM and a weak antitrypanosomal activity with an IC 50 of 37.6136 µM. The cytotoxicity of 1 was evaluated using standard experimental procedures against THP1 cells and no cytotoxicity was observed indicating its selectivity and safety.Supplemental data for this article can be accessed here.