Symptom → Plant Sources

Ashwagandha (Withania somnifera) and Immune support: evidence and sources

Preliminary evidence

For educational purposes only, not medical advice. Always consult a qualified practitioner before using medicinal plants, especially alongside prescribed medication, during pregnancy, or for a serious condition.

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https://ods.od.nih.gov/factsheets/Ashwagandha-HealthProfessional/

National Institutes of Health Office of Dietary Supplements. Ashwagandha: Is it helpful for stress, anxiety, or sleep? Health Professional Fact Sheet. 2024. https://ods.od.nih.gov/factsheets/Ashwagandha-HealthProfessional/ · 2024

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pmc.ncbi.nlm.nih.gov

Downer S, Berkowitz SA, Harlan TS, et al. Ashwagandha · 2023

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;6(1):20.

Bonilla DA, Moreno Y, Gho C, et al. Effects of ashwagandha · 2021

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;13(2):1557988319835985.

Lopresti AL, Drummond PD, Smith SJ. A randomized, double-blind, placebo-controlled, crossover study examining the hormonal and vitality effects of ashwagandha · 2019

Traditional / referenceAjagandhaAsgandAshwagandhaIndian GinsengKanaje Hindi+2 moreWithania somnifera

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pmc.ncbi.nlm.nih.gov

Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha · 2019

Traditional / referenceAjagandhaAsgandAshwagandhaIndian GinsengKanaje Hindi+2 moreWithania somnifera

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;11(12):e6466.

Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults: A double-blind, randomized, placebo-controlled clinical study. Cureus. 2019;11 · 2019

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;34(3):255-262.

Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012;34 · 2012

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;8(5 Suppl):208-213.

Singh N, Bhalla M, de Jager P, Gilca M. An overview on ashwagandha: A Rasayana · 2011

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8 sources supporting Ashwagandha for Immune support. Includes scientific publications, books, monographs and traditional-use references.

Mechanistic basis

This use is associated with the plant's immunomodulator / immune support action.