Symptom → Plant Sources
Hop (Humulus lupulus) as a tool for helping with Arthritis / joint pain
inferred from anti-inflammatory action
3 sources supporting Hop for Arthritis / joint pain. Includes scientific publications, books, monographs and traditional-use references.
Mechanistic basis
This use is associated with the plant's anti-inflammatory action. Further evidence for that pharmacology:
Humulus lupulus extract showed anti-inflammatory and anti-oxidative effects on solar-simulator-irradiated human keratinocytes (reducing ERK/p38 MAPK phosphorylation and IL-6/IL-8), with its in-vivo anti-inflammatory efficacy depending on the topical galenic formulation.
Spent-hops (Humulus lupulus) extract modulated the inflammatory response of LPS-stimulated RAW 264.7 macrophages, reducing pro-inflammatory mediators and demonstrating an anti-inflammatory action of hops by-products.