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Nephroprotective effect of cranberry (Vaccinium oxycoccos) in streptozocin-induced diabetic nephropathy in mice

Shareef, S.M., Khaleel, R.A. and Maryoosh, T.M. · Drug Metabolism and Personalized Therapy · 2024

Preclinical

Abstract

A hydroalcoholic extract of cranberry (Vaccinium oxycoccos) was tested in streptozotocin-induced diabetic nephropathy in mice. The extract improved serum and urine renal parameters, raised antioxidant enzymes (SOD, GSH) and lowered inflammatory cytokines (TNF-alpha, IL-6, TGF-beta1), demonstrating antioxidant, anti-inflammatory and nephroprotective effects.

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How to cite

Shareef, S.M., Khaleel, R.A. and Maryoosh, T.M (2024) 'Nephroprotective effect of cranberry (Vaccinium oxycoccos) in streptozocin-induced diabetic nephropathy in mice', Drug Metabolism and Personalized Therapy, 39(1), pp. 35-45. doi:10.1515/dmpt-2023-0092

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