Novel Quinic Acid Glycerates from Tussilago farfara Inhibit Polypeptide GalNAc-Transferase

Feng, J., Zhang, Y., Qin, X., Gao, T. and others · ChemBioChem · 2022

Preclinical

Abstract

Novel quinic acid glycerates were isolated from Tussilago farfara and identified as inhibitors of human polypeptide N-acetylgalactosaminyltransferases (GalNAc-Ts), the initiating enzymes of mucin-type O-glycosylation, adding new bioactive constituents to the known chemistry of coltsfoot.

Referenced for these plants

2020 2020)Coltsfoot Common coltsfoot Kuan Dong Hua / Farfarae Flos (Chen et al Liu et al coughwort foal’s foot horsehoofTussilago farfara

How to cite

Feng, J., Zhang, Y., Qin, X., Gao, T. and others (2022) 'Novel Quinic Acid Glycerates from Tussilago farfara Inhibit Polypeptide GalNAc-Transferase', ChemBioChem, 23(3), pp. e202100539. doi:10.1002/cbic.202100539

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