Rumex acetosa L. induces vasorelaxation in rat aorta via activation of PI3-kinase/Akt- and Ca2+-eNOS-NO signaling in endothelial cells

Sun, Y.Y., Su, X.H., Jin, J.Y., Zhou, J. and others · Journal of Physiology and Pharmacology · 2015

Preclinical

Abstract

Rumex acetosa, an important traditional medicine, was tested for vascular effects. The extract induced endothelium-dependent vasorelaxation in rat aorta via activation of the PI3-kinase/Akt and Ca2+-eNOS-NO signalling pathways in endothelial cells, providing a mechanism for its cardiovascular use.

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How to cite

Sun, Y.Y., Su, X.H., Jin, J.Y., Zhou, J. and others (2015) 'Rumex acetosa L. induces vasorelaxation in rat aorta via activation of PI3-kinase/Akt- and Ca2+-eNOS-NO signaling in endothelial cells', Journal of Physiology and Pharmacology, 66(6), pp. 907-915. Available at: https://pubmed.ncbi.nlm.nih.gov/26769840/

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