← Reference Library

Rumex acetosa modulates platelet function and inhibits thrombus formation in rats

Jeong, D., Irfan, M., Kim, S.D., Kim, S. and others · BMC Complementary Medicine and Therapies · 2020

Preclinical

Abstract

Rumex acetosa, used in medicinal treatment and food in Eastern Asia, was examined for antiplatelet activity. The extract markedly inhibited collagen-induced platelet aggregation and ATP release dose-dependently, suppressed intracellular calcium mobilisation and integrin activation, and attenuated MAPK and PI3K/Akt signalling, suggesting it may protect against platelet-related cardiovascular disease.

Referenced for these plants

How to cite

Jeong, D., Irfan, M., Kim, S.D., Kim, S. and others (2020) 'Rumex acetosa modulates platelet function and inhibits thrombus formation in rats', BMC Complementary Medicine and Therapies, 20(1), pp. 98. doi:10.1186/s12906-020-02889-5

This reference is part of the evidence base for the Omnia Sana plant database. Source links open the original publication; Omnia Sana does not host third-party content.