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Phenolic and Iridoid Glycosides from Leonurus cardiaca L. and Their Effects on the alpha, delta, and gamma Subtypes of the PPAR System

Kuchta, K., Hladikova, J., Thomsen, M., Nguyen, A.D. and others · Molecules · 2025

Preclinical

Abstract

Leonurus cardiaca is known in Europe for its cardioactivity, also in relation to metabolic-syndrome risk factors. Phenolic and iridoid glycosides were isolated, including a novel phenylethanoid (cardiaphenyloside A), and tested on PPAR alpha, delta and gamma subtypes, identifying constituents that modulate the PPAR system relevant to anti-inflammatory and metabolic activity.

Referenced for these plants

How to cite

Kuchta, K., Hladikova, J., Thomsen, M., Nguyen, A.D. and others (2025) 'Phenolic and Iridoid Glycosides from Leonurus cardiaca L. and Their Effects on the alpha, delta, and gamma Subtypes of the PPAR System', Molecules, 30(2), pp. 419. doi:10.3390/molecules30020419

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