Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Abstract
A meta-analysis of 27 clinical trials (3808 patients) comparing St John's wort (Hypericum perforatum) with SSRIs in depression. St John's wort demonstrated comparable response and remission rates and significantly lower discontinuation/dropout than standard SSRIs, supporting comparable efficacy and safety for mild-to-moderate depression; evidence on long-term efficacy and use in severe depression remains limited.
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How to cite
Ng, Q.X., Venkatanarayanan, N. and Ho, C.Y.X (2017) 'Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis', Journal of Affective Disorders, 210, pp. 211-221. doi:10.1016/j.jad.2016.12.048
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