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Comprehensive Metabolomic Profiling and Biological Activity Analysis of Eschscholzia californica Extracts Using LC-ESI-QTOF-MS

Kalyniukova, A., Ahmed, S., Ak, G., Saka, E. et al. · Food Science & Nutrition · 2025

Preclinical

Abstract

LC-ESI-QTOF-MS profiling of Eschscholzia californica aerial-part extracts identified 70 compounds including rutin, quinoline alkaloids, morphine derivatives and scoulerine. Extracts showed antioxidant, anti-acetylcholinesterase, anti-tyrosinase and anti-glucosidase activity, and in silico studies showed protopine, rutin, eschscholtzidine, boldine and scoulerine inhibit insomnia-related DRD5, DRD4 and SERT proteins, supporting the plant's traditional use for sleep.

Referenced for these plants

How to cite

Kalyniukova, A., Ahmed, S., Ak, G., Saka, E. et al (2025) 'Comprehensive Metabolomic Profiling and Biological Activity Analysis of Eschscholzia californica Extracts Using LC-ESI-QTOF-MS', Food Science & Nutrition, 13(9), pp. e70885. doi:10.1002/fsn3.70885

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