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New 8,12;8,20-diepoxy-8,14-secopregnane hexa- and hepta-glycosides from the roots of Asclepias tuberosa

Warashina, T. and Miyase, T. · Journal of Natural Medicines · 2017

Preclinical

Abstract

Phytochemical investigation of the roots of Asclepias tuberosa (Asclepiadaceae) afforded eight new minor 8,12;8,20-diepoxy-8,14-secopregnane glycosides consisting of six or seven 2,6-dideoxy-hexopyranoses together with the aglycone tuberogenin. The structures were established using NMR, mass spectrometry and chemical evidence. These secopregnane-type glycosides, observed only in A. tuberosa, are considered characteristic phytochemicals of this plant (pleurisy root).

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How to cite

Warashina, T. and Miyase, T (2017) 'New 8,12;8,20-diepoxy-8,14-secopregnane hexa- and hepta-glycosides from the roots of Asclepias tuberosa', Journal of Natural Medicines, 72(1), pp. 347-356. doi:10.1007/s11418-017-1155-9

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