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Artemisia absinthium Extract Attenuates the Quinolinic Acid-Induced Cell Injury in OLN-93 Cells

Rashidi, R., Akaberi, M., Gholoobi, A., Ghazavi, H. and Forouzanfar, F. · Current Drug Discovery Technologies · 2023

Preclinical

Abstract

Quinolinic acid (QA) accumulation is found in many neurodegenerative diseases. Artemisia absinthium has neuroprotective and antioxidant activities. In OLN-93 cells, pretreatment with A. absinthium extract prevented the loss of cell viability and reduced reactive oxygen species generation, lipid peroxidation and apoptosis in QA-injured cells, exerting a neuroprotective effect via oxidative stress and apoptosis modulation.

Referenced for these plants

How to cite

Rashidi, R., Akaberi, M., Gholoobi, A., Ghazavi, H. and Forouzanfar, F (2023) 'Artemisia absinthium Extract Attenuates the Quinolinic Acid-Induced Cell Injury in OLN-93 Cells', Current Drug Discovery Technologies, 20(4), pp. e300323215213. doi:10.2174/1570163820666230330105331

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