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Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L.

Gao, Q., Yang, M. and Zuo, Z. · Acta Pharmacologica Sinica · 2018

Traditional / reference

Abstract

Arctigenin and its glycoside arctiin are two major active ingredients of Arctium lappa L., a popular medicinal herb and health supplement frequently used in Asia. This article reviews their anti-inflammatory effects, pharmacokinetics and clinical efficacies. Arctigenin exhibits potent anti-inflammatory activities by inhibiting iNOS via modulation of several cytokines and may serve as a potential therapeutic compound against acute inflammation and various chronic diseases.

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How to cite

Gao, Q., Yang, M. and Zuo, Z (2018) 'Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L', Acta Pharmacologica Sinica, 39(5), pp. 787-801. doi:10.1038/aps.2018.32

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