Effect ofPlantago majoron Burn Wound Healing in Rat

Abstract

Abstract Amini, M., Kherad, M., Mehrabani, D., Azarpira, N., Panjehshahin, M.R. and Tanideh, N. 2010. Effect of Plantago major on burn wound healing in rat. J. Appl. Anim. Res., 37: 53–56. To determine the effect of Plantago major on healing of burn wounds, 100 male Sprague-Dawley 180–220 g rats were randomly divided into 4 groups. Groups of A, B and C each comprised of 30 rats, which were treated with silver sulfadiazine, 20% and 50% Plantago major solution. Group D comprised of 10 rats, which were considered as control group and were treated with Oserin. After 7, 14 and 21 d of treatment, the animals were sacrificed, burn areas were examined histopathologically and scored. There was no significant difference between groups on d 7 and 14 but the difference was significant on d 21. The best results were noticed in group C receiving 50% P. major solution. So Plantago major may be a suitable substitute for silver sulfadiazine especially when applied in 50% concentration. Keywords: Silver sulfadiazine Plantago major woundhealingepithelializationrat