Omnia SanaA new capsaicin-containing phenolic glycoside from Capsicum annuum L.
Abstract
A new N -containing phenolic glycoside ( 1 ) and seven known compounds were isolated from the fruits of Capsicum annuum L. Their structures were elucidated by extensive spectroscopic methods including MS, 1D and 2D NMR (HSQC, HMBC, 1 H- 1 H COSY, etc.). The stereo configuration of the new compound was determined by comparison of the experimental and calculated electronic circular dichroism (ECD) spectra. Compounds 1-8 were evaluated in vitro for their cytotoxic activities against HCT-116 cell line using Sulforhodamine B (SRB) assay, and the result showed only compound 6 displayed a weak inhibitory activity against HCT-116 (IC 50 = 22.5 ± 3.3 mmol/mL).
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How to cite
Song, C., Yu, C., Zhu, X., Luo, X., Zhang, Y., Meng, L., Luo, Y., Chang, H., Qin, C. and Liu, Y (2020) 'A new capsaicin-containing phenolic glycoside from Capsicum annuum L', Natural Product Research, 36(2), pp. 546-552. doi:10.1080/14786419.2020.1789983
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