Hamamelitannin from witch hazel (Hamamelis virginiana) displays specific cytotoxic activity against colon cancer cells

Sanchez-Tena, S., Fernandez-Cachon, M.L., Carreras, A., Mateos-Martin, M.L., Costoya, N., Moyer, M.P., Nunez, M.J., Torres, J.L. and Cascante, M. · Journal of Natural Products · 2012

Preclinical

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Abstract

Hamamelitannin from Hamamelis virginiana bark showed selective cytotoxic activity against colon cancer cells (apoptosis, S-phase arrest) without harming normal colonocytes, indicating an anticancer potential of witch hazel tannins.

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How to cite

Sanchez-Tena, S., Fernandez-Cachon, M.L., Carreras, A., Mateos-Martin, M.L., Costoya, N., Moyer, M.P., Nunez, M.J., Torres, J.L. and Cascante, M (2012) 'Hamamelitannin from witch hazel (Hamamelis virginiana) displays specific cytotoxic activity against colon cancer cells', Journal of Natural Products, 75(1), pp. 26-33. doi:10.1021/np200426k

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