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Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions

Russo, E., Scicchitano, F., Whalley, B.J., Mazzitello, C., Ciriaco, M., Esposito, S., Patane, M., Upton, R., Pugliese, M., Chimirri, S., Mammi, M., Palleria, C. and De Sarro, G. · Phytotherapy Research · 2013

Meta-analysis / review
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Abstract

This review details the pharmacokinetics, mechanism of action, tolerability and clinical drug-drug interactions of Hypericum perforatum, whose naphthodianthrones and phloroglucinols underpin its antidepressant use.

Referenced for these plants

Perforate St John’s-wortSt John's wortcommon St John's wortperforate St John's wortHypericum perforatum

How to cite

Russo, E., Scicchitano, F., Whalley, B.J., Mazzitello, C., Ciriaco, M., Esposito, S., Patane, M., Upton, R., Pugliese, M., Chimirri, S., Mammi, M., Palleria, C. and De Sarro, G (2013) 'Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions', Phytotherapy Research, 28(5), pp. 643-655. doi:10.1002/ptr.5050

This reference is part of the evidence base for the Omnia Sana plant database. Source links open the original publication; Omnia Sana does not host third-party content.

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