Artemisia absinthium and Artemisia vulgaris: a comparative study of infusion polysaccharides

Abstract

The aerial parts of Artemisia absinthium and Artemisia vulgaris are used in infusions for the treatment of several diseases. Besides secondary metabolites, carbohydrates are also extracted with hot water and are present in the infusions. The plant carbohydrates exhibit several of therapeutic properties and their biological functions are related to chemical structure. In this study, the polysaccharides from infusions of the aerial parts of A. absinthium and A. vulgaris were isolated and characterized. In the A. absinthium infusion, a type II arabinogalactan was isolated. The polysaccharide had a Gal:Ara ratio of 2.3:1, and most of the galactose was (1 → 3)- and (1 → 6)-linked, as typically found in type II arabinogalactans. In the A. vulgaris infusion, an inulin-type fructan was the main polysaccharide. NMR analysis confirmed the structure of the polymer, which is composed of a chain of fructosyl units β-(2 ← 1) linked to a starting α-d-glucose unit.