Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation

Wang, S., Dunlap, T.L., Howell, C.E., Mbachu, O.C., Rue, E.A. and Phansalkar, R. · Chemical Research in Toxicology · 2016

Preclinical

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Abstract

Humulus lupulus (hops) extract and its prenylflavonoid 6-prenylnaringenin induced P450 1A1-catalysed estrogen 2-hydroxylation, a chemoprotective shift in estrogen metabolism relevant to the use of hops for menopausal symptoms.

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How to cite

Wang, S., Dunlap, T.L., Howell, C.E., Mbachu, O.C., Rue, E.A. and Phansalkar, R (2016) 'Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation', Chemical Research in Toxicology, 29(7), pp. 1142-1150. doi:10.1021/acs.chemrestox.6b00112

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