Humulus lupulus L. extract and its active constituent xanthohumol attenuate oxidative stress and nerve injury induced by iron overload via activating AKT/GSK3beta and Nrf2/NQO1 pathways
Abstract
Humulus lupulus (hops) extract and its prenylflavonoid xanthohumol attenuated iron-overload-induced oxidative stress and nerve injury by activating the AKT/GSK3beta and Nrf2/NQO1 antioxidant pathways, demonstrating a neuroprotective antioxidant effect.
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How to cite
Sun, X.L., Xia, T.S., Jiang, Y.P., Wang, N.N., Xu, L.C. and Han, T (2022) 'Humulus lupulus L. extract and its active constituent xanthohumol attenuate oxidative stress and nerve injury induced by iron overload via activating AKT/GSK3beta and Nrf2/NQO1 pathways', Journal of Natural Medicines, 76(4), pp. 801-814. doi:10.1007/s11418-022-01642-1
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