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Modulatory effects of artichoke (Cynara scolymus L.) leaf extract against oxidative stress and hepatic TNF-alpha gene expression in acute diazinon-induced liver injury in rats

Ahmadi, A., Heidarian, E. and Ghatreh-Samani, K. · Journal of Basic and Clinical Physiology and Pharmacology · 2019

Preclinical

Abstract

Artichoke (Cynara scolymus) leaf extract protected rat liver against diazinon-induced injury, reducing serum liver enzymes, malondialdehyde, TNF-alpha and hepatic TNF-alpha gene expression while improving antioxidant enzyme activity and histopathology, confirming its hepatoprotective action.

Referenced for these plants

How to cite

Ahmadi, A., Heidarian, E. and Ghatreh-Samani, K (2019) 'Modulatory effects of artichoke (Cynara scolymus L.) leaf extract against oxidative stress and hepatic TNF-alpha gene expression in acute diazinon-induced liver injury in rats', Journal of Basic and Clinical Physiology and Pharmacology, 30(5), pp. 20180180. doi:10.1515/jbcpp-2018-0180

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