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The effect of Cynara scolymus (artichoke) on maternal reproductive outcomes and fetal development in rats

Gotardo, A.T., Mattos, M.I.S., Hueza, I.M. and Gorniak, S.L. · Regulatory Toxicology and Pharmacology · 2019

Preclinical

Abstract

In Wistar rats, dry extract of Cynara scolymus leaves administered during gestation reduced fetal weight and length and litter size at higher doses (without malformations), indicating that artichoke consumption during pregnancy can negatively affect fetuses - an important safety consideration.

Referenced for these plants

How to cite

Gotardo, A.T., Mattos, M.I.S., Hueza, I.M. and Gorniak, S.L (2019) 'The effect of Cynara scolymus (artichoke) on maternal reproductive outcomes and fetal development in rats', Regulatory Toxicology and Pharmacology, 102, pp. 74-78. doi:10.1016/j.yrtph.2019.01.004

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