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Vitex Agnus-Castus for the Treatment of Cyclic Mastalgia: A Systematic Review and Meta-Analysis

Ooi, S.L., Watts, S., McClean, R. and Pak, S.C. · Journal of Women's Health · 2020

Meta-analysis / review

Abstract

This systematic review and meta-analysis of 25 studies found Vitex agnus-castus effective in relieving cyclic mastalgia breast-pain intensity and lowering elevated serum prolactin (via dopaminergic activity), with a moderate effect size favouring it over placebo and non-inferiority to pharmaceutical comparators.

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How to cite

Ooi, S.L., Watts, S., McClean, R. and Pak, S.C (2020) 'Vitex Agnus-Castus for the Treatment of Cyclic Mastalgia: A Systematic Review and Meta-Analysis', Journal of Women's Health, 29(2), pp. 262-278. doi:10.1089/jwh.2019.7770

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