Design of an Herbal Preparation Composed by a Combination of Ruscus aculeatus L. and Vitis vinifera L. Extracts, Magnolol and Diosmetin to Address Chronic Venous Diseases through an Anti-Inflammatory Effect and AP-1 Modulation
Abstract
A herbal preparation based on Ruscus aculeatus root extract (with Vitis vinifera, diosmetin and magnolol) reduced cytokine secretion from LPS-stimulated endothelial cells and nearly abolished AP-1 and NF-kappaB activation, demonstrating an anti-inflammatory mechanism relevant to chronic venous disease.
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How to cite
Nocera, R., Eletto, D., Santoro, V., Parisi, V. and others (2023) 'Design of an Herbal Preparation Composed by a Combination of Ruscus aculeatus L. and Vitis vinifera L. Extracts, Magnolol and Diosmetin to Address Chronic Venous Diseases through an Anti-Inflammatory Effect and AP-1 Modulation', Plants, 12(5), pp. 1051. doi:10.3390/plants12051051
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