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Liquid-liquid chromatography isolation of Petasites hybridus sesquiterpenes and their LC-HR-MS/MS and NMR characterization

Kulinowski, L., Luca, S.V., Pecio, L., Minceva, M. and Skalicka-Wozniak, K. · Journal of Pharmaceutical and Biomedical Analysis · 2023

Preclinical

Abstract

This study isolated and characterised the major bioactive sesquiterpenes of butterbur (Petasites hybridus) - including petasin and isopetasin - by liquid-liquid chromatography and spectroscopy, providing reference standards for standardisation and pharmacological evaluation.

Referenced for these plants

How to cite

Kulinowski, L., Luca, S.V., Pecio, L., Minceva, M. and Skalicka-Wozniak, K (2023) 'Liquid-liquid chromatography isolation of Petasites hybridus sesquiterpenes and their LC-HR-MS/MS and NMR characterization', Journal of Pharmaceutical and Biomedical Analysis, 234, pp. 115529. doi:10.1016/j.jpba.2023.115529

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