Pharmacokinetic Herb-Drug Interaction between Essential Oil of Aniseed (Pimpinella anisum L., Apiaceae) and Acetaminophen and Caffeine: A Potential Risk for Clinical Practice

Samojlik, I., Petkovic, S., Stilinovic, N., Vukmirovic, S. and others · Phytotherapy Research · 2016

Preclinical

Abstract

Aniseed (Pimpinella anisum) essential oil altered the pharmacokinetics of acetaminophen and caffeine in rats, indicating a potential herb-drug interaction relevant to the safe medicinal use of anise.

Referenced for these plants

Anise Anise seed AniseedPimpinella anisum

How to cite

Samojlik, I., Petkovic, S., Stilinovic, N., Vukmirovic, S. and others (2016) 'Pharmacokinetic Herb-Drug Interaction between Essential Oil of Aniseed (Pimpinella anisum L., Apiaceae) and Acetaminophen and Caffeine: A Potential Risk for Clinical Practice', Phytotherapy Research, 30(2), pp. 253-259. doi:10.1002/ptr.5523

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