Tilia species (linden) exert anti-cancer effects on MIA PaCa-2 cells through the modulation of oxidative stress and inflammation

Yuksel, G., Ozhan, Y., Guresci, D., Guzelmeric, E. and others · Scientific Reports · 2025

Preclinical

Abstract

Extracts of Tilia species including T. cordata flowers and bracts displayed remarkable antioxidant activity, inhibited LPS-induced nitrite, IL-6 and PGE2 production (anti-inflammatory) and showed anticancer effects on pancreatic cancer cells, supporting the bioactivity of linden.

Referenced for these plants

How to cite

Yuksel, G., Ozhan, Y., Guresci, D., Guzelmeric, E. and others (2025) 'Tilia species (linden) exert anti-cancer effects on MIA PaCa-2 cells through the modulation of oxidative stress and inflammation', Scientific Reports, 15(1), pp. 2317. doi:10.1038/s41598-025-86457-2

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