Safety of medicinal comfrey cream preparations (Symphytum officinale s.l.): The pyrrolizidine alkaloid lycopsamine is poorly absorbed through human skin
Preclinical
Abstract
Lycopsamine, the main pyrrolizidine alkaloid of comfrey (Symphytum officinale), was shown to be poorly absorbed through human skin, supporting the safety of external medicinal comfrey cream preparations within recommended limits.
Referenced for these plants
How to cite
Kuchta, K. and Schmidt, M (2020) 'Safety of medicinal comfrey cream preparations (Symphytum officinale s.l.): The pyrrolizidine alkaloid lycopsamine is poorly absorbed through human skin', Regulatory Toxicology and Pharmacology, 118, pp. 104784. doi:10.1016/j.yrtph.2020.104784
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