Role of Nitric Oxide and Hydrogen Sulfide in the Vasodilator Effect of Ursolic Acid and Uvaol from Black Cherry Prunus serotina Fruits

Luna-Vazquez, F.J., Ibarra-Alvarado, C., Rojas-Molina, A., Romo-Mancillas, A. and others · Molecules · 2016

Preclinical

Abstract

Ursolic acid and uvaol, isolated from black cherry (Prunus serotina) fruits, produced significant endothelium-dependent vasodilation (smooth-muscle relaxation) in rat aorta via the NO/cGMP and H2S/KATP channel pathways, providing a mechanism relevant to the antispasmodic use of wild cherry.

Referenced for these plants

How to cite

Luna-Vazquez, F.J., Ibarra-Alvarado, C., Rojas-Molina, A., Romo-Mancillas, A. and others (2016) 'Role of Nitric Oxide and Hydrogen Sulfide in the Vasodilator Effect of Ursolic Acid and Uvaol from Black Cherry Prunus serotina Fruits', Molecules, 21(1), pp. 78. doi:10.3390/molecules21010078

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