Journal

Lions mane

July 2, 2026 · Omnia Sana
Hericium erinaceus
Family: Hericiaceae  ·  Parts used: Fruit, Mycelium  ·  Also known as: Lauvas krēpes

Key actions

Anti-inflammatoryDigestive aidImmunomodulator / immune supportNeuroprotective / cognition support

Traditional & clinical uses, by strength of evidence

  • Cognitive functionGood
  • MemoryGood
  • Arthritis / joint painModerate
  • BloatingModerate
  • Cold & fluModerate
  • Immune supportModerate
  • IndigestionModerate
  • Inflammation (general)Moderate
  • Skin irritationModerate

Selected studies & references

ReviewLion's Mane Mushroom (Hericium erinaceus): A Neuroprotective Fungus with Antioxidant, Anti-Inflammatory, and Antimicrobial Potential – A Narrative Review (2025)
ReviewChemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion's Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds (2015)
RctAcute effects of a standardised extract of Hericium erinaceus (Lion's Mane mushroom) on cognition and mood in healthy younger adults: a double-blind randomised placebo-controlled study (2025)
RctThe Acute and Chronic Effects of Lion's Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study (2023)
RctImproving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial (2009)
ClinicalPrevention of Early Alzheimer's Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study (2020)
PreclinicalPolysaccharides from an edible mushroom, Hericium erinaceus, alleviate ulcerative colitis in mice by inhibiting the NLRP3 inflammasomes and reestablish intestinal homeostasis (2024)
PreclinicalPolysaccharides from Hericium erinaceus and its immunomodulatory effects on RAW 264.7 macrophages (2024)

All 13 studies in the Knowledge Finder →

Educational use only. This profile summarises traditional and scientific sources for reference. It is not medical advice and not a substitute for a qualified practitioner. Some plants carry safety cautions and drug interactions — always check before use.

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