Plant Comparison
Wild Cherry Bark vs Raspberry Leaf
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Wild Cherry Bark and Raspberry Leaf: both belong to the Rosaceae family; they share 1 indicated use (menstrual cramps).
Evidence face-off — shared uses
| Condition | Wild Cherry Bark | Raspberry Leaf | Verdict |
|---|---|---|---|
| Menstrual cramps | 1/10 | 5/10 | Stronger for Raspberry Leaf |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Releases trace hydrogen cyanide that calms the cough reflex - the basis of both the antitussive action and the safety caution.
Astringent and aromatic supporting constituents.
Bio-guided fractionation of the bark identified naringenin and trimethoxy-benzene/benzoic-acid compounds; the bark extract also showed antiparasitic (cysticidal) activity in laboratory studies.
Pharmacological Actions
Astringent for mild diarrhoea (tannins)
Astringent for menstrual cramps (traditional); Astringent for mild diarrhoea (tannins)
Traditional uterine tonic taken in late pregnancy to tone the uterus and support labour - one small double-blind RCT found a shorter second stage of labour and fewer forceps deliveries (no effect on the first stage), alongside observational signals; robust proof is still lacking
Traditional & Indicated Uses
Antispasmodic for bronchial cough and bronchitis (eases spasm of the airways)
inferred from anticancer action
Antispasmodic for bronchial cough and bronchitis (eases spasm of the airways); Antitussive - calms a persistent dry, irritating cough (prunasin quietens the cough reflex)
inferred from antispasmodic action
inferred from antispasmodic action
Astringent for menstrual cramps (traditional)
inferred from emmenagogue action
inferred from astringent action
Safety, Cautions & Contraindications
Contains cyanogenic compounds: use only properly dried, prepared bark and avoid large or prolonged doses (fresh bark has a higher toxic content). It suppresses the cough reflex, so it suits dry, unproductive coughs - not productive coughs where mucus needs clearing.
Avoid in pregnancy and breastfeeding because of the cyanogenic glycosides.
External Ids
Botanical Description
Deciduous tree (Rosaceae), 15-30 m tall, with dark, scaly, aromatic bark that has a distinctive bitter-almond smell when cut or crushed (from cyanogenic compounds). Leaves are glossy dark green, elliptical and finely toothed. Small white flowers are borne in drooping racemes, followed by small, dark purple-black cherries that are edible when fully ripe but otherwise bitter.[12]
Deciduous, thicket-forming shrub (Rosaceae), 1-2 m tall, with upright, prickly, biennial canes (vegetative in the first year, fruiting in the second). Leaves are pinnate with 3-7 toothed leaflets, whitish-felted beneath. Small white, five-petalled flowers are followed by the aggregate red raspberry fruit, a cluster of drupelets.[2]
Habitat
Native to eastern North America, growing in a wide range of woodland, forest-edge and open habitats on well-drained soils; widely naturalised and, in parts of Europe, considered an invasive tree.[12]
Native to Europe and northern Asia, widely cultivated as a fruit crop and naturalised on woodland edges, hedgerows and disturbed ground in temperate regions.[2]
Harvesting
Bark is stripped from the trunk and larger branches, traditionally in autumn, and must be thoroughly dried before use - fresh bark has a much higher cyanogenic-glycoside content and is more toxic.[13]
Leaves are picked fresh during the growing season - before or during flowering is considered optimal - and dried; fruit is picked when fully ripe in summer.[2]
Traditional Uses
Wild cherry bark has a long Native American and European settler tradition as a cough remedy, valued specifically for its unusual cough-suppressant action - from the cyanogenic glycoside prunasin, which releases a trace, sedating amount of cyanide that calms the cough reflex. It remains a classic ingredient of traditional cough syrups.[12, 13]
Raspberry leaf has a long, very widely known folk tradition as a 'pregnancy tea', taken in the final weeks of pregnancy as a uterine tonic to prepare for labour. Observational studies and a small randomised controlled trial suggest a possible modest effect on labour duration, though robust proof is still lacking.[1, 13]
Preparations
Dosage
Traditional guidance suggests roughly 1-2 g dried bark per cup as a decoction, up to three times daily, using only properly dried bark; avoid large or prolonged doses given the cyanogenic-glycoside content, and avoid in pregnancy and breastfeeding. Educational reference only, not a prescription.
Popular guidance and observational studies generally describe starting raspberry-leaf tea or tablets in the last few weeks of pregnancy, at roughly 1-3 cups of tea daily; use should be discussed with a midwife or doctor given the lack of robust trial evidence. Educational reference only, not a prescription.
References
Lookalikes Review
References & Sources
- Telichowska, A., Kobus-Cisowska, J. and Szulc, P (2020) 'Phytopharmacological Possibilities of Bird Cherry Prunus padus L. and Prunus serotina L. Species and Their Bioactive Phytochemicals', Nutrients, 12(7), pp. 1966. doi:10.3390/nu12071966 Traditional / reference
https://doi.org/10.3390/nu12071966 - Luna-Vazquez, F.J., Ibarra-Alvarado, C., Rojas-Molina, A., Romo-Mancillas, A. and others (2016) 'Role of Nitric Oxide and Hydrogen Sulfide in the Vasodilator Effect of Ursolic Acid and Uvaol from Black Cherry Prunus serotina Fruits', Molecules, 21(1), pp. 78. doi:10.3390/molecules21010078 Preclinical
https://doi.org/10.3390/molecules21010078 - Palomares-Alonso, F., Rojas-Tome, I.S., Palencia Hernandez, G., Jimenez-Arellanes, M.A., Macias-Rubalcava, M.L. and others (2017) 'In vitro and in vivo cysticidal activity of extracts and isolated flavanone from the bark of Prunus serotina: A bio-guided study', Acta Tropica, pp. 1--7. doi:10.1016/j.actatropica.2017.02.023 Preclinical
https://doi.org/10.1016/j.actatropica.2017.02.023 - Robakowski, P., Bielinis, E., Stachowiak, J., Mejza, I. and Bulaj, B (2016) 'Seasonal Changes Affect Root Prunasin Concentration in Prunus serotina and Override Species Interactions between P. serotina and Quercus petraea', Journal of Chemical Ecology, 42(3), pp. 202-214. doi:10.1007/s10886-016-0678-y Preclinical
https://doi.org/10.1007/s10886-016-0678-y - Gallardo-Rivera, C.T., Lu, A., Trevino-Garza, M.Z., Garcia-Marquez, E. and others (2021) 'Valorization of Capulin Almond (Prunus serotina) by Obtaining Bioactive Compounds', Frontiers in Nutrition, 8, pp. 663953. doi:10.3389/fnut.2021.663953 Preclinical
https://doi.org/10.3389/fnut.2021.663953 - Sile, I., Videja, M., Makrecka-Kuka, M., Tirzite, D. and others (2020) 'Chemical composition of Prunus padus L. flower extract and its anti-inflammatory activities in primary bone marrow-derived macrophages', Journal of Ethnopharmacology, 268, pp. 113678. doi:10.1016/j.jep.2020.113678 Preclinical
https://doi.org/10.1016/j.jep.2020.113678 - Olszewska, M.A. and Kwapisz, A (2011) 'Metabolite profiling and antioxidant activity of Prunus padus L. flowers and leaves', Natural Product Research, 25(12), pp. 1115-1131. doi:10.1080/14786410903230359 Preclinical
https://doi.org/10.1080/14786410903230359 - Santos Pimenta, L.P., Schilthuizen, M., Verpoorte, R. and Choi, Y.H (2013) 'Quantitative analysis of amygdalin and prunasin in Prunus serotina Ehrh. using 1H-NMR spectroscopy', Phytochemical Analysis, 25(2), pp. 122-126. doi:10.1002/pca.2476 Preclinical
https://doi.org/10.1002/pca.2476 - Rivero-Cruz, B (2014) 'Simultaneous quantification by HPLC of the phenolic compounds for the crude drug of Prunus serotina subsp. capuli', Pharmaceutical Biology, 52(8), pp. 1015-1020. doi:10.3109/13880209.2013.876054 Preclinical
https://doi.org/10.3109/13880209.2013.876054 - Yamaguchi, K., Liggett, J.L., Kim, N.C. and Baek, S.J (2006) 'Anti-proliferative effect of horehound leaf and wild cherry bark extracts on human colorectal cancer cells', Oncology Reports, 15(1), pp. 275-281. doi:10.3892/or.15.1.275 Preclinical
https://doi.org/10.3892/or.15.1.275 - Alvarez-Suarez, J.M., Carrillo-Perdomo, E., Aller, A., Giampieri, F., Gasparrini, M., Gonzalez-Perez, L., Beltran-Ayala, P. and Battino, M (2017) 'Anti-inflammatory effect of Capuli cherry against LPS-induced cytotoxic damage in RAW 264.7 macrophages', Food and Chemical Toxicology, 102, pp. 46-52. doi:10.1016/j.fct.2017.01.024 Preclinical
https://doi.org/10.1016/j.fct.2017.01.024 - Herbal Reality (n.d.) 'Wild Cherry (Prunus serotina): Benefits, Uses, Research'. Available at: https://www.herbalreality.com/herb/wild-cherry/ Traditional / reference
https://www.herbalreality.com/herb/wild-cherry/ - The Herbal Medic (n.d.) 'Wild Cherry Bark (Prunus serotina) - Soothing Herb for Coughs & Lungs'. Available at: https://theherbalmedic.co.uk/wild-cherry-prunus-serotina Traditional / reference
https://theherbalmedic.co.uk/wild-cherry-prunus-serotina
- Bowman, R.L., Taylor, J. and Davis, D.L (2024) 'Raspberry leaf (Rubus idaeus) use in pregnancy: a prospective observational study', BMC Complementary Medicine and Therapies. doi:10.1186/s12906-024-04465-7 Randomized trial
https://doi.org/10.1186/s12906-024-04465-7 - Mostafa, H.S. and others (2020) 'Phenolic Composition, Mineral Content, and Beneficial Bioactivities of Leaf Extracts from Black Currant (Ribes nigrum L.), Raspberry (Rubus idaeus), and Aronia (Aronia melanocarpa)', Nutrients, 12(2), pp. 463. doi:10.3390/nu12020463 Meta-analysis / review
https://doi.org/10.3390/nu12020463 - Bijak, M., Saluk-Bijak, J. and others (2016) 'The influence of Rubus idaeus and Rubus caesius leaf extracts on platelet aggregation in whole blood. Cross-talk of platelets and neutrophils', Platelets, 27(5), pp. 433-439. doi:10.3109/09537104.2015.1131254 Preclinical
https://doi.org/10.3109/09537104.2015.1131254 - Valdes, M. and others (2022) 'Rubus idaeus extract improves symptoms in knee osteoarthritis patients: results from a phase II double-blind randomized controlled trial', BMC Musculoskeletal Disorders, 23(1), pp. 650. doi:10.1186/s12891-022-05612-2 Randomized trial
https://doi.org/10.1186/s12891-022-05612-2 - Campos, P.M. and others (2020) 'Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial', Journal of Cosmetic Dermatology, 19(3), pp. 671-676. doi:10.1111/jocd.13305 Randomized trial
https://doi.org/10.1111/jocd.13305 - Bednarski, M. and others (2014) 'CD39/NTPDase-1 expression and activity in human umbilical vein endothelial cells are differentially regulated by leaf extracts from Rubus caesius and Rubus idaeus', Cellular & Molecular Biology Letters, 19(2), pp. 291-304. doi:10.2478/s11658-014-0202-8 Preclinical
https://doi.org/10.2478/s11658-014-0202-8 - Rojas-Vera, J., Patel, A.V. and Dacke, C.G (2002) 'Relaxant activity of raspberry (Rubus idaeus) leaf extract in guinea-pig ileum in vitro', Phytotherapy Research, 16(7), pp. 665-668. doi:10.1002/ptr.1040 Preclinical
https://doi.org/10.1002/ptr.1040 - Raudone, L. and others (2022) 'In Vitro Antioxidant and Prooxidant Activities of Red Raspberry (Rubus idaeus L.) Stem Extracts', Molecules, 27(13), pp. 4073. doi:10.3390/molecules27134073 Preclinical
https://doi.org/10.3390/molecules27134073 - Cugnetto, M.L. and others (2015) 'An oil-soluble extract of Rubus idaeus cells enhances hydration and water homeostasis in skin cells', International Journal of Cosmetic Science, 37(4), pp. 428-433. doi:10.1111/ics.12236 Preclinical
https://doi.org/10.1111/ics.12236 - Socha, M.W., Flis, W., Wartega, M., Szambelan, M., Pietrus, M. and Kazdepka-Zieminska, A (2023) 'Raspberry Leaves and Extracts-Molecular Mechanism of Action and Its Effectiveness on Human Cervical Ripening and the Induction of Labor', Nutrients, 15(14), pp. 3206. doi:10.3390/nu15143206 Clinical study
https://doi.org/10.3390/nu15143206 - Jianu, E.M., Pop, R.M., Gherman, L.M., Ranga, F., Levai, A.M., Rus, V., Bolboaca, S.D., Stefan, R.A., Onofrei, M.M., Nati, I.D., Stoia, I.A., Stefan, P.A., Mihu, C. and Mihu, C.M (2024) 'The Effect of Rubus idaeus Polyphenols Extract in Induced Endometriosis in Rats', Molecules, 29(4), pp. 778. doi:10.3390/molecules29040778 Preclinical
https://doi.org/10.3390/molecules29040778 - Cyboran-Mikolajczyk, S., Meczarska, K., Solarska-Sciuk, K., Ratajczak-Wielgomas, K., Oszmianski, J., Jencova, V. and Bonarska-Kujawa, D (2022) 'Protection of Erythrocytes and Microvascular Endothelial Cells against Oxidative Damage by Fragaria vesca L. and Rubus idaeus L. Leaves Extracts - The Mechanism of Action', Molecules, 27(18), pp. 5865. doi:10.3390/molecules27185865 Preclinical
https://doi.org/10.3390/molecules27185865 - Farnaghi, S. and Braniff, K (2022) 'Survey of Raspberry Leaf Tea in pregnancy', Australian and New Zealand Journal of Obstetrics and Gynaecology. doi:10.1111/ajo.13496 Randomized trial
https://doi.org/10.1111/ajo.13496 - Simpson, M., Parsons, M., Greenwood, J. and Wade, K (2001) 'Raspberry leaf in pregnancy: its safety and efficacy in labor', Journal of Midwifery & Women's Health, 46(2), pp. 51--59. doi:10.1016/s1526-9523(01)00095-2 Randomized trial
https://doi.org/10.1016/s1526-9523(01)00095-2
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.