Plant Comparison
Peppermint vs White clover
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Peppermint and White clover: they share 8 indicated uses (arthritis / joint pain, infection (general), inflammation (general), …); 6 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Peppermint | White clover | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 5/10 | 1/10 | Stronger for Peppermint |
| Infection (general) | 5/10 | 2/10 | Stronger for Peppermint |
| Inflammation (general) | 5/10 | 2/10 | Stronger for Peppermint |
| Menstrual cramps | 5/10 | 1/10 | Stronger for Peppermint |
| Muscle spasm | 5/10 | 1/10 | Stronger for Peppermint |
| Skin irritation | 5/10 | 1/10 | Stronger for Peppermint |
| Wounds | 5/10 | 7/10 | Stronger for White clover |
| Cognitive function | 2/10 | 2/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Menthol is the dominant constituent of the leaf oil, responsible for the cooling sensation and much of the antispasmodic and analgesic activity.
Phenolic antioxidants of the leaf.
Present in small amounts; not significant in normal food or tea use.
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from antispasmodic action
inferred from antispasmodic action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from anticancer action
inferred from immunomodulator action
inferred from anti-inflammatory action
inferred from antispasmodic action
inferred from antispasmodic action
inferred from anti-inflammatory action
inferred from antimicrobial action
Safety, Cautions & Contraindications
Generally very safe. Essential oil should not be applied to the face or chest of infants or children — menthol can cause respiratory depression. Avoid enteric-coated capsules if taking antacids or acid-suppressing drugs. May worsen GERD by relaxing the lower oesophageal sphincter. Avoid in bile duct obstruction and gallstones.
Duke (2002) rates peppermint as +++ with clinical evidence (score 2) for antispasmodic activity, consistent with Commission E approval for IBS (irritable bowel syndrome) using enteric-coated peppermint oil capsules. Enteric-coated peppermint oil is one of the most clinically validated herbal treatments for IBS, reducing abdominal pain and spasm. Dose: 0.6 ml enteric-coated oil two to three times daily between meals (for IBS); 1.5–3 g dried leaf as tea three times daily for digestive complaints. Peppermint should not be applied near the face or nostrils of infants and small children (risk of laryngospasm from menthol). Contraindicated in cholelithiasis (gallstones) (Duke, 2002).
Generally very safe as a food and in moderate herbal use. Cyanogenic glucosides present in very small amounts — not significant in normal food or tea use. Isoflavones are phytoestrogens (as in red clover) — same precautions apply in hormone-sensitive conditions. Well tolerated by most people.
External Ids
Botanical Description
Perennial herb, 30-90 cm tall, a sterile natural hybrid (Mentha aquatica x M. spicata) that spreads by rhizomes and surface stolons rather than viable seed. Stems are square, often purple-tinged. Leaves are opposite, lance-shaped to ovate with a sharply toothed margin, and release a strong menthol scent when crushed. Small, pale purple flowers are borne in dense, interrupted terminal spikes.[2]
Low, creeping perennial herb rooting at the nodes, with trifoliate leaves, each leaflet oval and often marked with a pale chevron. Rounded white (sometimes pink-tinged) flower heads are borne on long stalks above the foliage.[30]
Habitat
A cultivated hybrid grown worldwide as a crop and garden herb, propagated vegetatively since it rarely sets viable seed; naturalised in damp ground - streambanks, ditches and waste places - in temperate regions.[2]
Grows in lawns, pastures, meadows and grassy waste ground; native to Europe and western Asia and now naturalised worldwide, including as a common lawn and forage plant.[30]
Harvesting
Aerial parts are cut at or just before full flowering (mid- to late summer), when the essential-oil (menthol) content peaks, then dried quickly out of direct sun, or distilled fresh for essential oil.[3]
Flowering heads and leaves are picked through the flowering season and dried in a warm, shaded, airy place.[30]
Traditional Uses
Peppermint has one of the best-documented traditional uses of any herb - as a carminative and antispasmodic for indigestion, bloating and colic. Enteric-coated peppermint oil capsules are among the most clinically validated herbal treatments for irritable bowel syndrome, and topical or inhaled peppermint oil is traditionally and clinically used for tension-type headache and muscular aches.[1, 2, 4, 5]
White clover has a folk tradition, similar to but lighter than its relative red clover, as an anti-inflammatory and wound-healing remedy and mild expectorant, and modern research on its isoflavones and phenolics has additionally investigated antioxidant, kidney-protective and liver-protective activity.[30, 31, 32]
Preparations
Dried leaf steeped in hot water, the classic digestive tea.
Standardised peppermint oil in enteric-coated capsules, the clinically studied form for irritable bowel syndrome, releasing the oil in the intestine rather than the stomach.
Diluted essential oil applied to the temples and neck for tension-type headache.
Dried flower and leaf infused in hot water as a traditional mild tonic and expectorant tea.
Dosage
Duke (2002) and Commission E guidance: about 0.6 mL enteric-coated oil two to three times daily between meals for IBS-type digestive complaints. Educational reference only, not a prescription.
Not documented
References
Lookalikes Review
References & Sources
- McKay, D.L. and Blumberg, J.B (2006) 'A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.)', Phytotherapy Research, 20(8), pp. 619-633. doi:10.1002/ptr.1936 Meta-analysis / review
https://doi.org/10.1002/ptr.1936 - Mahendran, G. and Rahman, L.U (2020) 'Ethnomedicinal, phytochemical and pharmacological updates on Peppermint (Mentha x piperita L.)-A review', Phytotherapy Research, 34(9), pp. 2088-2139. doi:10.1002/ptr.6664 Meta-analysis / review
https://doi.org/10.1002/ptr.6664 - Zhao, H., Ren, S., Yang, H., Tang, S. and others (2022) 'Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application', Biomedicine & Pharmacotherapy, 154, pp. 113559. doi:10.1016/j.biopha.2022.113559 Meta-analysis / review
https://doi.org/10.1016/j.biopha.2022.113559 - Keifer, D., Ulbricht, C., Abrams, T.R., Basch, E. and others (2007) 'Peppermint (Mentha piperita): an evidence-based systematic review by the Natural Standard Research Collaboration', Journal of Herbal Pharmacotherapy, 7(2), pp. 91-143. doi:10.1300/j157v07n02_07 Meta-analysis / review
https://doi.org/10.1300/j157v07n02_07 - Gobel, H., Heinze, A., Heinze-Kuhn, K., Gobel, A. and Gobel, C (2016) 'Peppermint oil in the acute treatment of tension-type headache', Schmerz, 30(3), pp. 295-310. doi:10.1007/s00482-016-0109-6 Meta-analysis / review
https://doi.org/10.1007/s00482-016-0109-6 - Nair, B (2001) 'Final report on the safety assessment of Mentha Piperita (Peppermint) Oil, Mentha Piperita (Peppermint) Leaf Extract, Mentha Piperita (Peppermint) Leaf, and Mentha Piperita (Peppermint) Leaf Water', International Journal of Toxicology, 20(Suppl 3), pp. 61-73. doi:10.1080/10915810152902592 Meta-analysis / review
https://doi.org/10.1080/10915810152902592 - Kobayashi, T., Sugaya, K., Onose, J. and Abe, N (2019) 'Peppermint (Mentha piperita) extract effectively inhibits cytochrome P450 3A4 (CYP3A4) mRNA induction in rifampicin-treated HepG2 cells', Bioscience, Biotechnology, and Biochemistry, 83(7), pp. 1181-1192. doi:10.1080/09168451.2019.1608802 Preclinical
https://doi.org/10.1080/09168451.2019.1608802 - Romero, M.C., Navarro, M.C., Martin-Sanchez, J. and Valero, A (2014) 'Peppermint (Mentha piperita) and albendazole against anisakiasis in an animal model', Tropical Medicine & International Health, 19(12), pp. 1430-1436. doi:10.1111/tmi.12399 Preclinical
https://doi.org/10.1111/tmi.12399 - Riachi, L.G. and De Maria, C.A.B (2015) 'Peppermint antioxidants revisited', Food Chemistry, 176, pp. 72-81. doi:10.1016/j.foodchem.2014.12.028 Meta-analysis / review
https://doi.org/10.1016/j.foodchem.2014.12.028 - Herro, E. and Jacob, S.E (2010) 'Mentha piperita (peppermint)', Dermatitis, 21(6), pp. 327-329. doi:10.2310/6620.2011.10080 Preclinical
https://doi.org/10.2310/6620.2011.10080 - Sun, Z. and Wang, H. and Wang, J. and Zhou, L. and Yang, P (2014) 'Chemical Composition and Anti-Inflammatory, Cytotoxic and Antioxidant Activities of Essential Oil from Leaves of Mentha piperita Grown in China', PLoS ONE. doi:10.1371/journal.pone.0114767 Preclinical
https://doi.org/10.1371/journal.pone.0114767 - Farco, J.A. and Grundmann, O (2012) 'Menthol - Pharmacology of an Important Naturally Medicinal “Cool”', Mini-Reviews in Medicinal Chemistry. doi:10.2174/138955713804484686 Preclinical
https://doi.org/10.2174/138955713804484686 - Geuenich, S. and Goffinet, C. and Venzke, S. and Nolkemper, S. and Baumann, I. and Plinkert, P.K. and Reichling, J. and Keppler, O.T (2008) 'Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density', Retrovirology. doi:10.1186/1742-4690-5-27 Preclinical
https://doi.org/10.1186/1742-4690-5-27 - Nolkemper, S. and Reichling, J. and Stintzing, F.C. and Carle, R. and Schnitzler, P (2006) 'Antiviral Effect of Aqueous Extracts from Species of the Lamiaceae Family against Herpes simplex Virus Type 1 and Type 2 in vitro', Planta Medica. doi:10.1055/s-2006-951719 Preclinical
https://doi.org/10.1055/s-2006-951719 - Mahady, G.B. and Pendland, S.L. and Stoia, A. and Hamill, F.A. and Fabricant, D.G. and Dietz, B.M. and Chadwick, L.R (2005) 'In Vitro susceptibility ofHelicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders', Phytotherapy Research. doi:10.1002/ptr.1776 Preclinical
https://doi.org/10.1002/ptr.1776 - Tullio, V.C. and Roana, J. and Scalas, D. and Mandras, N (2019) 'Evaluation of the Antifungal Activity of Mentha x piperita (Lamiaceae) of Pancalieri (Turin, Italy) Essential Oil and Its Synergistic Interaction with Azoles', Molecules. doi:10.3390/molecules24173148 Preclinical
https://doi.org/10.3390/molecules24173148 - Neves, A. and Rosa, S. and Gonçalves, J. and Rufino, A.T. and Judas, F. and Salgueiro, L. and Lopes, M.C. and Cavaleiro, C. and Mendes, A (2009) 'Screening of Five Essential Oils for Identification of Potential Inhibitors of IL-1-induced Nf-κB Activation and NO Production in Human Chondrocytes: Characterization of the Inhibitory Activity ofα-Pinene', Planta Medica. doi:10.1055/s-0029-1186085 Preclinical
https://doi.org/10.1055/s-0029-1186085 - Wu, Z. and Tan, B. and Liu, Y. and Dunn, J.L. and Guerola, P.M. and Tortajada, M. and Cao, Z. and Ji, P (2019) 'Chemical Composition and Antioxidant Properties of Essential Oils from Peppermint, Native Spearmint and Scotch Spearmint', Molecules. doi:10.3390/molecules24152825 Preclinical
https://doi.org/10.3390/molecules24152825 - Bojić, M. and Maleš, Ž. and Antolić, A. and Babić, I. and Tomičić, M (2019) 'Antithrombotic activity of flavonoids and polyphenols rich plant species', Acta Pharmaceutica. doi:10.2478/acph-2019-0050 Preclinical
https://doi.org/10.2478/acph-2019-0050 - Dorman, H.J.D. and Koşar, M. and Kahlos, K. and Holm, Y. and Hiltunen, R (2003) 'Antioxidant Properties and Composition of Aqueous Extracts from Mentha Species, Hybrids, Varieties, and Cultivars', Journal of Agricultural and Food Chemistry. doi:10.1021/jf034108k Preclinical
https://doi.org/10.1021/jf034108k - Benabdallah, A. and Boumendjel, M. and Aissi, O. and Rahmoune, C. and Boussaïd, M. and Messaoud, C (2018) 'Chemical composition, antioxidant activity and acetylcholinesterase inhibitory of wild Mentha species from northeastern Algeria', South African Journal of Botany. doi:10.1016/j.sajb.2018.03.002 Preclinical
https://doi.org/10.1016/j.sajb.2018.03.002 - Ayaz, M. and Sadiq, A. and Junaid, M. and Ullah, F. and Subhan, F. and Ahmed, J (2017) 'Neuroprotective and Anti-Aging Potentials of Essential Oils from Aromatic and Medicinal Plants', Frontiers in Aging Neuroscience. doi:10.3389/fnagi.2017.00168 Clinical study
https://doi.org/10.3389/fnagi.2017.00168 - Vladimir‐Knežević, S. and Blažeković, B. and Kindl, M. and Vladić, J. and Lower-Nedza, A.D. and Brantner, A (2014) 'Acetylcholinesterase Inhibitory, Antioxidant and Phytochemical Properties of Selected Medicinal Plants of the Lamiaceae Family', Molecules. doi:10.3390/molecules19010767 Preclinical
https://doi.org/10.3390/molecules19010767 - López, V. and Martin, S.D. and Gómez‐Serranillos, M.P. and Carretero, M. and Jäger, A.K. and Calvo, M.I (2009) 'Neuroprotective and neurochemical properties of mint extracts', Phytotherapy Research. doi:10.1002/ptr.3037 Preclinical
https://doi.org/10.1002/ptr.3037 - Orhan, İ.E. and Kartal, M. and Kan, Y. and Şener, B (2008) 'Activity of Essential Oils and Individual Components against Acetyland Butyrylcholinesterase', Zeitschrift für Naturforschung C. doi:10.1515/znc-2008-7-813 Preclinical
https://doi.org/10.1515/znc-2008-7-813 - Zeljkovıć, S.Ć. and Šišková, J. and Komzáková, K. and Diego, N.D. and Kaffková, K. and Tarkowski, P (2021) 'Phenolic Compounds and Biological Activity of Selected Mentha Species', Plants. doi:10.3390/plants10030550 Preclinical
https://doi.org/10.3390/plants10030550 - Desam, N.R. and Al-Rajab, A.J. and Sharma, M. and Mylabathula, M.M. and Gowkanapalli, R.R. and Albratty, M (2017) 'Chemical constituents, in vitro antibacterial and antifungal activity of Mentha×Piperita L. (peppermint) essential oils', Journal of King Saud University - Science. doi:10.1016/j.jksus.2017.07.013 Preclinical
https://doi.org/10.1016/j.jksus.2017.07.013 - Husain, F.M. and Ahmad, I. and Khan, M.S. and Ahmad, E. and Tahseen, Q. and Khan, M.S. and Al‐Shabib, N.A (2015) 'Sub-MICs of Mentha piperita essential oil and menthol inhibits AHL mediated quorum sensing and biofilm of Gram-negative bacteria', Frontiers in Microbiology. doi:10.3389/fmicb.2015.00420 Preclinical
https://doi.org/10.3389/fmicb.2015.00420 - Khayyal, M.T. and El‐Ghazaly, M.A. and Kenawy, S.A. and Seif-El-Nasr, M. and Mahran, L. and Kafafi, Y. and Okpanyi, S (2011) 'Antiulcerogenic Effect of Some Gastrointestinally Acting Plant Extracts and their Combination', Arzneimittelforschung. doi:10.1055/s-0031-1300078 Preclinical
https://doi.org/10.1055/s-0031-1300078 - Singh, R. and Shushni, M.A.M. and Belkheir, A.K (2011) 'Antibacterial and antioxidant activities of Mentha piperita L', Arabian Journal of Chemistry. doi:10.1016/j.arabjc.2011.01.019 Preclinical
https://doi.org/10.1016/j.arabjc.2011.01.019 - Dorman, H.J.D. and Koşar, M. and Başer, K.H.C. and Hiltunen, R (2009) 'Phenolic Profile and Antioxidant Evaluation of Mentha x Piperita L. (Peppermint) Extracts', Natural Product Communications. doi:10.1177/1934578x0900400419 Preclinical
https://doi.org/10.1177/1934578x0900400419 - İşcan, G. and Kırımer, N. and Kürkçüoğlu, M. and Başer, H.C. and Demi̇rci̇, F (2002) 'Antimicrobial Screening of Mentha piperita Essential Oils', Journal of Agricultural and Food Chemistry. doi:10.1021/jf011476k Preclinical
https://doi.org/10.1021/jf011476k - Akdogan, M. et al (2004) 'Investigation of biochemical and histopathological effects of Mentha piperita labiatae and Mentha spicata labiatae on kidney tissue in rats', 23(7), pp. 321--327. Preclinical
https://scholar.google.com/scholar?q=Investigation%20of%20biochemical%20and%20histopathological%20effects%20of%20Mentha%20piperita%20labiatae%20and%20Mentha%20spicata%20labiatae%20on%20kidney%20tissue%20in%20rats - Grigoleit, H.G. and Grigoleit, P (2005) 'Peppermint oil in irritable bowel syndrome', 12(8), pp. 601--606. Randomized trial
https://scholar.google.com/scholar?q=Peppermint%20oil%20in%20irritable%20bowel%20syndrome - Mas-Coma, S (2004) 'Fasciolosis in humans'. Traditional / reference
https://scholar.google.com/scholar?q=Fasciolosis%20in%20humans - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
- Ngangom, L., Venugopal, D. and Pandey, N (2024) 'Investigation of Trifolium repens L. from the Indian Himalayan region as a phyto-therapeutic agent', Natural Product Research, 38(24), pp. 4468-4478. doi:10.1080/14786419.2023.2299319 Meta-analysis / review
https://doi.org/10.1080/14786419.2023.2299319 - Ahmad, S. and Zeb, A (2020) 'Phytochemical profile and pharmacological properties of Trifolium repens', Journal of Basic and Clinical Physiology and Pharmacology, 32(3), pp. 20200015. doi:10.1515/jbcpp-2020-0015 Meta-analysis / review
https://doi.org/10.1515/jbcpp-2020-0015 - Sarno, F., Pepe, G., Termolino, P., Carafa, V. and others (2020) 'Trifolium repens Blocks Proliferation in Chronic Myelogenous Leukemia via the BCR-ABL/STAT5 Pathway', Cells, 9(2), pp. 379. doi:10.3390/cells9020379 Preclinical
https://doi.org/10.3390/cells9020379 - Ahmad, S. and Zeb, A (2020) 'Nephroprotective property of Trifolium repens leaf extract against paracetamol-induced kidney damage in mice', 3 Biotech, 10(12), pp. 541. doi:10.1007/s13205-020-02539-0 Preclinical
https://doi.org/10.1007/s13205-020-02539-0 - Kolodziejczyk-Czepas, J (2012) 'Trifolium species-derived substances and extracts--biological activity and prospects for medicinal applications', Journal of Ethnopharmacology, 143(1), pp. 14-23. doi:10.1016/j.jep.2012.06.048 Meta-analysis / review
https://doi.org/10.1016/j.jep.2012.06.048 - Chen, Y.H., Chen, P., Wang, Y., Yang, C.H., Wu, X., Wu, C.J., Luo, L., Wang, Q., Niu, C. and Yao, J.Y (2019) 'Structural characterization and anti-inflammatory activity evaluation of chemical constituents in the extract of Trifolium repens L', Journal of Food Biochemistry, 43(9), pp. e12981. doi:10.1111/jfbc.12981 Preclinical
https://doi.org/10.1111/jfbc.12981 - Habibi Zadeh, S.K., Farahpour, M.R. and Kar, H.H (2020) 'The effect of topical administration of an ointment prepared from Trifolium repens hydroethanolic extract on the acceleration of excisional cutaneous wound healing', Wounds, 32(9), pp. 253-261. doi:10.25270/wnds/2020.253261 Preclinical
https://doi.org/10.25270/wnds/2020.253261 - Kicel, A. and Wolbis, M (2012) 'Study on the phenolic constituents of the flowers and leaves of Trifolium repens L', Natural Product Research, 26(21), pp. 2050-2054. doi:10.1080/14786419.2011.637217 Preclinical
https://doi.org/10.1080/14786419.2011.637217 - Ahmad, S. and Zeb, A (2019) 'Effects of phenolic compounds from aqueous extract of Trifolium repens against acetaminophen-induced hepatotoxicity in mice', Journal of Food Biochemistry, 43(9), pp. e12963. doi:10.1111/jfbc.12963 Preclinical
https://doi.org/10.1111/jfbc.12963 - Borczak, B. and Szewczyk, A. and Domagała, D. and Kapusta-Duch, J. and Leszczyńska, T. and Kotuła, M. and Grulova, D (2024) 'Potential Antidiabetic, Antioxidative and Antiproliferative Properties of Functional Wheat Flour Muffins Enriched with White Clover Flowers (Trifolium repens L.)', Int J Mol Sci, 25(18). doi:10.3390/ijms25189909 Preclinical
https://doi.org/10.3390/ijms25189909 - Rawat, P. and Kumar, B. and Misra, A. and Singh, S.P. and Singh, S.P. and Srivastava, S (2025) 'Effect of hydrolysed Trifolium repens L. extract on menopause-induced obesity and depressive symptoms: an in vitro and in vivo approach', Nat Prod Res, pp. 1-8. doi:10.1080/14786419.2025.2560636 Preclinical
https://doi.org/10.1080/14786419.2025.2560636 - Parić, A. and Mesic, A. and Mahmutović-Dizdarević, I. and Jerković-Mujkić, A. and Žujo, B. and Bašić, N. and Pustahija, F (2024) 'Bioactive potential of Trifolium repens L. essential oil', J Environ Sci Health B, 59(9), pp. 584-594. doi:10.1080/03601234.2024.2396730 Preclinical
https://doi.org/10.1080/03601234.2024.2396730 - Renda, G. and Yalçın, F.N. and Nemutlu, E. and Akkol, E.K. and Süntar, I. and Keleş, H. and Ina, H. and Çalış, I. and Ersöz, T (2013) 'Comparative assessment of dermal wound healing potentials of various Trifolium L. extracts and determination of their isoflavone contents as potential active ingredients', J Ethnopharmacol, 148(2), pp. 423-32. doi:10.1016/j.jep.2013.04.031 Preclinical
https://doi.org/10.1016/j.jep.2013.04.031 - Ahmed, I.A.M. and Matthäus, B. and Özcan, M.M. and Juhaimi, F.A. and Ghafoor, K. and Babiker, E.E. and Osman, M.A. and Alqah, H.A.S (2020) 'Determination of Bioactive Lipid and Antioxidant Activity of Onobrychis, Pimpinella, Trifolium, and Phleum spp. Seed and Oils', J Oleo Sci, 69(11), pp. 1367-1371. doi:10.5650/jos.ess20153 Preclinical
https://doi.org/10.5650/jos.ess20153 - Harlow, B.E. and Flythe, M.D. and Goodman, J.P. and Ji, H. and Aiken, G.E (2022) 'Isoflavone Containing Legumes Mitigate Ergot Alkaloid-Induced Vasoconstriction in Goats (Capra hircus)', Animals (Basel), 12(6). doi:10.3390/ani12060750 Preclinical
https://doi.org/10.3390/ani12060750 - Shang, H. and Li, R. and Wu, H. and Sun, Z (2019) 'Polysaccharides from Trifolium repens L. extracted by different methods and extraction condition optimization', Sci Rep, 9(1), pp. 6353. doi:10.1038/s41598-019-42877-5 Preclinical
https://doi.org/10.1038/s41598-019-42877-5 - Prati, S. and Baravelli, V. and Fabbri, D. and Schwarzinger, C. and Brandolini, V. and Maietti, A. and Tedeschi, P. and Benvenuti, S. and Macchia, M. and Marotti, I. and Bonetti, A. and Catizone, P. and Dinelli, G (2007) 'Composition and content of seed flavonoids in forage and grain legume crops', J Sep Sci, 30(4), pp. 491-501. doi:10.1002/jssc.200600383 Preclinical
https://doi.org/10.1002/jssc.200600383 - Woolsey, I.D. and Zeller, W.E. and Blomstrand, B.M. and Øines, Ø. and Enemark, H.L (2022) 'Effects of selected condensed tannins on Cryptosporidium parvum growth and proliferation in HCT-8 cell cultures', Exp Parasitol, 241, pp. 108353. doi:10.1016/j.exppara.2022.108353 Preclinical
https://doi.org/10.1016/j.exppara.2022.108353 - Hou, K. and Xue, Q. and Shi, L. and Liu, S. and Zhong, X. and Liu, Y. and Wang, C (2026) 'Identification of Trifolium repens as a New Source of Glycyrrhetinic Acid: Pathway Elucidation and Heterologous Reconstruction in Yeast', J Agric Food Chem, 74(19), pp. 15182-15194. doi:10.1021/acs.jafc.6c02001 Preclinical
https://doi.org/10.1021/acs.jafc.6c02001 - Tundis, R. and Marrelli, M. and Conforti, F. and Tenuta, M.C. and Bonesi, M. and Menichini, F. and Loizzo, M.R (2015) 'Trifolium pratense and T. repens (Leguminosae): Edible Flower Extracts as Functional Ingredients', Foods, 4(3), pp. 338-348. doi:10.3390/foods4030338 Preclinical
https://doi.org/10.3390/foods4030338 - Başar, Y. and Yıldız, İ. and HOSAFLIOĞLU, İ. and Azeroual, A. and Erenler, R (2026) 'The Phytochemical Content and DPPH Activity of Trifolium repens L. Methanol Extract, and In Silico Studies', Adıyaman üniversitesi fen bilimleri dergisi, 16(1), pp. 61-76. doi:10.37094/adyujsci.1813336 Preclinical
https://doi.org/10.37094/adyujsci.1813336 - Ayoubi, S.A. and Abdelwahab, I. and Ela, M.A. and Lakany, A.E. and Raafat, K (2026) 'Advanced Hybrid-Green Ultrasound–Infrared–Microwave Trifolium repens Essential oil Isolation with Multi-Target Ethnomedicine Bioactivity against Neuropathy, Inflammation and Multidrug-Resistant Infection', Journal of Food and Drug Analysis, 34(2). doi:10.38212/2224-6614.3595 Preclinical
https://doi.org/10.38212/2224-6614.3595 - Ahmad, S. and Zeb, A. and Ayaz, M. and Murkovic, M (2019) 'Characterization of phenolic compounds using UPLC–HRMS and HPLC–DAD and anti-cholinesterase and anti-oxidant activities of Trifolium repens L. leaves', European Food Research and Technology, 246(3), pp. 485-496. doi:10.1007/s00217-019-03416-8 Preclinical
https://doi.org/10.1007/s00217-019-03416-8 - Petrović, M. and Stanković, M. and Anđelković, B. and Babić, S. and Zornić, V. and Vasiljević, S. and Stevanović, Z.D (2016) 'Quality Parameters and Antioxidant Activity of Three Clover Species in Relation to the Livestock Diet', Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 44(1), pp. 201-208. doi:10.15835/nbha44110144 Preclinical
https://doi.org/10.15835/nbha44110144 - Jakubczyk, K. and Łukomska, A. and Gutowska, I. and Kochman, J. and Janił, J. and Janda, K (2021) 'Edible Flowers Extracts as a Source of Bioactive Compounds with Antioxidant Properties—In Vitro Studies', Applied Sciences, 11(5), pp. 2120-2120. doi:10.3390/app11052120 Preclinical
https://doi.org/10.3390/app11052120 - Ngangom, L. and Venugopal, D. and Pandey, N. and Kumar, N (2022) 'In-silico screening and identification of potential bioactive compounds of Trifolium repens against pathogenic bacterial target proteins', Materials Today Proceedings, 73, pp. 142-150. doi:10.1016/j.matpr.2022.09.501 Preclinical
https://doi.org/10.1016/j.matpr.2022.09.501 - Amer, B. and Juul, L. and Møller, A.H. and Møller, H.S. and Dalsgaard, T.K (2020) 'Improved solubility of proteins from white and red clover – inhibition of redox enzymes', International Journal of Food Science & Technology, 56(1), pp. 302-311. doi:10.1111/ijfs.14632 Preclinical
https://doi.org/10.1111/ijfs.14632 - Pap, N. and Granato, D. and Järvenpää, E. and Tienaho, J. and Marnila, P. and Hellström, J. and Pihlava, J. and Franco, M. and Stefański, T. and Rinne, M (2024) 'Biorefining of legume and grass biomasses: Technological properties and bioactivities of the green juice', Future Foods, 9, pp. 100331-100331. doi:10.1016/j.fufo.2024.100331 Preclinical
https://doi.org/10.1016/j.fufo.2024.100331 - Ahn, C. and Lee, J. and Park, M.J. and Kim, J. and Yang, J. and Yoo, Y. and Jeung, E (2020) 'Cytostatic effects of plant essential oils on human skin and lung cells', Experimental and Therapeutic Medicine, 19(3), pp. 2008-2018. doi:10.3892/etm.2020.8460 Preclinical
https://doi.org/10.3892/etm.2020.8460 - Bhattacharya, S. et al (2013) 'Review of the botanical, phytochemical, pharmacological and toxicological properties of white clover (Trifolium repens L.)', 7(7), pp. 583--588. Traditional / reference
https://scholar.google.com/scholar?q=Review%20of%20the%20botanical%2C%20phytochemical%2C%20pharmacological%20and%20toxicological%20properties%20of%20white%20clover%20%28Trifolium%20repens%20L.%29 - Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
https://scholar.google.com/scholar?q=A%20Modern%20Herbal - Klaiber, I. et al (2002) 'Health benefits of isoflavones from clover species', 16(1), pp. 1--8. Traditional / reference
https://scholar.google.com/scholar?q=Health%20benefits%20of%20isoflavones%20from%20clover%20species - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.