Plant Comparison

White Dead Nettle vs Peppermint

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant AWhite Dead NettleLamium albumLamiaceaeFull monograph →
Plant BPeppermintMentha × piperitaLamiaceaeFull monograph →

At a glance

White Dead Nettle and Peppermint: both belong to the Lamiaceae family; they share 5 indicated uses (arthritis / joint pain, inflammation (general), respiratory support, …); 2 pharmacological actions in common.

White Dead NettlePeppermint
Constituents33
Pharmacological actions511
Indicated uses914
Safety notes42
Cited sources2636
Indicated uses
Only White Dead Nettle
BronchitisBruisingCoughDiarrhoea
Shared (5)
Arthritis / joint painInflammation (general)Respiratory supportSkin irritationWounds
Only Peppermint
Back painBloatingHeadacheIndigestionInfection (general)Menstrual crampsMuscle spasmPain (general)Cognitive function
Pharmacological actions
Only White Dead Nettle
AstringentExpectorantVulnerary (wound healing)
Shared (2)
Anti-inflammatoryAntioxidant
Only Peppermint
Analgesic (pain relief)AntimicrobialAntispasmodicDigestive aidAnticancer (preclinical)AntiviralAntifungalNeuroprotective / cognition supportGastroprotective

Evidence face-off — shared uses

ConditionWhite Dead NettlePeppermintVerdict
Arthritis / joint pain2/105/10Stronger for Peppermint
Inflammation (general)2/105/10Stronger for Peppermint
Respiratory support1/105/10Stronger for Peppermint
Skin irritation2/105/10Stronger for Peppermint
Wounds1/105/10Stronger for Peppermint

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Phenylpropanoid and flavonoid glycosides[13]

Verbascoside, tiliroside and quercetin/kaempferol 3-O-glucosides in the flowers.

Verbascoside (acteoside)GlycosidesKaempferolFlavonoidsQuercetin
Iridoid glycosides[14]

Lamalbid, alboside A and B and caryoptoside; linked to antioxidant and anti-inflammatory activity.

Iridoid glycosidesGlycosides
Standardisation markers (Lamii albi flos)[15]

Lamalbid, chlorogenic acid, verbascoside, rutin and tiliroside, richest in the flowering tops.

Chlorogenic acidVerbascoside (acteoside)Rutin
Essential oil (menthol, menthone)[3]

Menthol is the dominant constituent of the leaf oil, responsible for the cooling sensation and much of the antispasmodic and analgesic activity.

Essential (volatile) oilMentholTerpenes / terpenoids
Rosmarinic acid and flavonoids (eriocitrin, luteolin)[9]

Phenolic antioxidants of the leaf.

Rosmarinic acidFlavonoidsLuteolin
Tannins[2]

Contribute mild astringency.

Tannins

Pharmacological Actions

Anti-inflammatory[1, 2, 6, 14, 15, 16, 17]

Astringent and anti-inflammatory infusion or tincture (flowering tops)

Parts: Flower, Aerial parts
Antioxidant[4, 13, 14]
Parts: Flower
Astringent[7, 15, 16, 17]

Astringent (catarrh, excessive menstrual or vaginal discharge); Astringent and anti-inflammatory infusion or tincture (flowering tops)

Parts: Flower, Aerial parts
Expectorant[8, 16, 18]
Parts: Flower
Vulnerary (wound healing)[11, 16, 17]

Vulnerary (minor wounds), applied topically

Parts: Leaf
Analgesic (pain relief)[2, 5, 33, 34, 35]
Anti-inflammatory[1, 2, 3, 11, 33, 34, 35]
Antimicrobial[1, 2, 3, 8, 15, 27, 28, 30, 32, 33, 34, 35]
Antioxidant[1, 2, 3, 9, 11, 18, 20, 26, 30, 31, 33, 34, 35]
Antispasmodic[1, 4, 33, 34, 35]

Antispasmodic (cramp easing)

Digestive aid[1, 2, 4, 33, 34, 35]
Anticancer (preclinical)[11]
Antiviral[13, 14]
Antifungal[16, 27]
Neuroprotective / cognition support[20, 21, 22, 23, 24, 25]
Gastroprotective[29]

Traditional & Indicated Uses

Arthritis / joint pain[14, 15, 16, 17]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Arthritis / joint pain
Bronchitis[16, 18]Traditional · 1/10

inferred from expectorant action

Evidence: 1
Label: Bronchitis
Bruising[16, 17]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Bruising
Cough[16, 17]Traditional · 1/10

Astringent (catarrh, excessive menstrual or vaginal discharge)

Evidence: 1
Label: Cough
Diarrhoea[15, 16, 17]Traditional · 2/10

inferred from astringent action

Evidence: 2
Label: Diarrhoea
Inflammation (general)[14, 15, 16, 17]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Inflammation (general)
Respiratory support[16, 18]Traditional · 1/10

inferred from expectorant action

Evidence: 1
Label: Respiratory support
Skin irritation[15, 16, 17]Traditional · 2/10

inferred from astringent action

Evidence: 2
Label: Skin irritation
Wounds[16, 17]Traditional · 1/10

Vulnerary (minor wounds), applied topically

Evidence: 1
Label: Wounds
Arthritis / joint pain[33, 34, 35]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Arthritis / joint pain
Back pain[33, 34, 35]Moderate · 5/10

inferred from analgesic action

Evidence: 5
Label: Back pain
Bloating[33, 34, 35]Moderate · 5/10

inferred from digestive action

Evidence: 5
Label: Bloating
Headache[5, 33, 34, 35]Good · 8/10

inferred from analgesic action

Evidence: 8
Label: Headache
Indigestion[33, 34, 35]Moderate · 5/10

inferred from digestive action

Evidence: 5
Label: Indigestion
Infection (general)[13, 33, 34, 35]Moderate · 5/10

inferred from antimicrobial action

Evidence: 5
Label: Infection (general)
Inflammation (general)[33, 34, 35]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Inflammation (general)
Menstrual cramps[33, 34, 35]Moderate · 5/10

inferred from antispasmodic action

Evidence: 5
Label: Menstrual cramps
Muscle spasm[33, 34, 35]Moderate · 5/10

inferred from antispasmodic action

Evidence: 5
Label: Muscle spasm
Pain (general)[33, 34, 35]Moderate · 5/10
Evidence: 5
Label: Pain (general)
Respiratory support[33, 34, 35]Moderate · 5/10
Evidence: 5
Label: Respiratory support
Skin irritation[33, 34, 35]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Skin irritation
Wounds[33, 34, 35]Moderate · 5/10

inferred from antimicrobial action

Evidence: 5
Label: Wounds
Cognitive function[21, 23, 24]Traditional · 2/10

Peppermint/Mentha showed acetylcholinesterase inhibition (cognition-relevant, preclinical).

Evidence: 2
Label: Cognitive function

Safety, Cautions & Contraindications

Safety note[19]Info

Generally regarded as safe in culinary amounts and at normal medicinal doses; unlike the stinging nettle it has no stinging hairs.

Safety note[16, 19]Caution

Medicinal use during pregnancy or breastfeeding should be approached cautiously, as for any traditional astringent.

Safety note[17, 20]Caution

Identify correctly before foraging (resembles stinging nettle before flowering and red dead-nettle); clinical evidence is limited, so it should not replace conventional treatment.

Safety note[21, 22, 23, 24, 25, 26]Info

Identification, distribution and horticultural references for Lamium album.

Safety note[33, 34, 35]Caution

Generally very safe. Essential oil should not be applied to the face or chest of infants or children — menthol can cause respiratory depression. Avoid enteric-coated capsules if taking antacids or acid-suppressing drugs. May worsen GERD by relaxing the lower oesophageal sphincter. Avoid in bile duct obstruction and gallstones.

Safety note[33, 34, 35, 36]Caution

Duke (2002) rates peppermint as +++ with clinical evidence (score 2) for antispasmodic activity, consistent with Commission E approval for IBS (irritable bowel syndrome) using enteric-coated peppermint oil capsules. Enteric-coated peppermint oil is one of the most clinically validated herbal treatments for IBS, reducing abdominal pain and spasm. Dose: 0.6 ml enteric-coated oil two to three times daily between meals (for IBS); 1.5–3 g dried leaf as tea three times daily for digestive complaints. Peppermint should not be applied near the face or nostrils of infants and small children (risk of laryngospasm from menthol). Contraindicated in cholelithiasis (gallstones) (Duke, 2002).

External Ids

Gbif: 2926683
Wikidata: Q157626
Gbif: 8707933

Botanical Description

Perennial herb closely resembling stinging nettle in leaf shape but entirely without stinging hairs. Square stems bear opposite, toothed, heart-shaped leaves, and whorls of white, hooded, two-lipped flowers cluster in the upper leaf axils.[15]

Height: 20-60 cm
Habit: Erect, clump-forming perennial herb
Leaves: Opposite, toothed, heart-shaped, resembling stinging nettle but without stinging hairs
Flowers: White, hooded, two-lipped, in dense whorls in the upper leaf axils
Stem: Square (typical of the mint family), unarmed (no stinging hairs)
Root: Creeping rhizome
Fruit: Small nutlet (typical of Lamiaceae)
Flowering Period: March-November (almost year-round in mild climates)

Perennial herb, 30-90 cm tall, a sterile natural hybrid (Mentha aquatica x M. spicata) that spreads by rhizomes and surface stolons rather than viable seed. Stems are square, often purple-tinged. Leaves are opposite, lance-shaped to ovate with a sharply toothed margin, and release a strong menthol scent when crushed. Small, pale purple flowers are borne in dense, interrupted terminal spikes.[2]

Height: 30-90 cm
Habit: Rhizomatous, mat-forming perennial herb, sterile hybrid
Leaves: Opposite, lance-shaped to ovate, sharply toothed, strongly menthol-scented
Flowers: Small, pale purple, in dense interrupted terminal spikes
Stem: Square, often purple-tinged
Root: Spreading rhizomes and surface stolons
Fruit: Rarely sets seed (sterile hybrid); propagated vegetatively
Flowering Period: July-September

Habitat

Grows in hedgerows, waste ground, gardens and roadsides on nitrogen-rich soils; native to Europe and temperate Asia, widely naturalised elsewhere.

A cultivated hybrid grown worldwide as a crop and garden herb, propagated vegetatively since it rarely sets viable seed; naturalised in damp ground - streambanks, ditches and waste places - in temperate regions.[2]

Harvesting

The flowering tops are picked as they open, largely through spring to autumn given the long flowering season, and dried in a warm, shaded, airy place; the standardisation markers are richest in the flowering tops specifically.[15]

Parts: Flower, Leaf, Aerial parts
Season: Spring through autumn, as flowers open

Aerial parts are cut at or just before full flowering (mid- to late summer), when the essential-oil (menthol) content peaks, then dried quickly out of direct sun, or distilled fresh for essential oil.[3]

Parts: Leaf, Flowering tops
Season: Mid- to late summer, at or just before flowering

Traditional Uses

White dead-nettle flower has a long European folk history as an astringent remedy for catarrh and excessive menstrual or vaginal discharge, and topically as a vulnerary wash for minor wounds; the young leaves and shoots have also traditionally been eaten as a cooked spring pot-herb.

Peppermint has one of the best-documented traditional uses of any herb - as a carminative and antispasmodic for indigestion, bloating and colic. Enteric-coated peppermint oil capsules are among the most clinically validated herbal treatments for irritable bowel syndrome, and topical or inhaled peppermint oil is traditionally and clinically used for tension-type headache and muscular aches.[1, 2, 4, 5]

References

REF-1746, REF-1747, REF-1748, REF-1749, REF-1750, REF-1751, REF-1752, REF-1753, REF-1754, REF-1755, REF-1756, REF-1757
REF-1203, REF-1204, REF-1205, REF-1206, REF-1207, REF-1208, REF-1209, REF-1210, REF-1211, REF-1212, REF-3037, REF-3038, REF-3039, REF-3040, REF-3041, REF-3042, REF-3043, REF-3044, REF-3045, REF-3046, REF-3047, REF-3048, REF-3049, REF-3050, REF-3051, REF-3052, REF-3053, REF-3054, REF-3055, REF-3056, REF-3057, REF-3058

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Preparations

Not documented

Infusion (tea)[1]

Dried leaf steeped in hot water, the classic digestive tea.

Enteric-coated oil capsules[4, 33, 34, 35]

Standardised peppermint oil in enteric-coated capsules, the clinically studied form for irritable bowel syndrome, releasing the oil in the intestine rather than the stomach.

Essential oil (topical)[5]

Diluted essential oil applied to the temples and neck for tension-type headache.

Dosage

Not documented

Enteric-coated oil capsules[33, 34, 35]

Duke (2002) and Commission E guidance: about 0.6 mL enteric-coated oil two to three times daily between meals for IBS-type digestive complaints. Educational reference only, not a prescription.

Dried leaf infusion[33, 34, 35]

Traditional guidance: about 1.5-3 g dried leaf as a tea, up to three times daily for digestive complaints. Educational reference only, not a prescription.

References & Sources

  1. Czerwinska, M.E., Swierczewska, A., Wozniak, M. and Kiss, A.K (2017) 'Bioassay-Guided Isolation of Iridoids and Phenylpropanoids from Aerial Parts of Lamium album and Their Anti-inflammatory Activity in Human Neutrophils', Planta Medica, 83(12-13), pp. 1011-1019. doi:10.1055/s-0043-107031 Preclinical
    https://doi.org/10.1055/s-0043-107031
  2. Czerwinska, M.E., Swierczewska, A. and Granica, S (2018) 'Bioactive Constituents of Lamium album L. as Inhibitors of Cytokine Secretion in Human Neutrophils', Molecules, 23(11), pp. 2770. doi:10.3390/molecules23112770 Preclinical
    https://doi.org/10.3390/molecules23112770
  3. Czerwinska, M.E., Kalinowska, E., Popowski, D. and Bazylko, A (2020) 'Lamalbid, Chlorogenic Acid, and Verbascoside as Tools for Standardization of Lamium album Flowers - Development and Validation of HPLC-DAD Method', Molecules, 25(7), pp. 1721. doi:10.3390/molecules25071721 Preclinical
    https://doi.org/10.3390/molecules25071721
  4. Sulborska, A., Konarska, A., Matysik-Wozniak, A., Dmitruk, M., Weryszko-Chmielewska, E., Skalska-Kaminska, A. and Rejdak, R (2020) 'Phenolic Constituents of Lamium album L. subsp. album Flowers: Anatomical, Histochemical, and Phytochemical Study', Molecules, 25(24), pp. 6025. doi:10.3390/molecules25246025 Preclinical
    https://doi.org/10.3390/molecules25246025
  5. Konarska, A., Weryszko-Chmielewska, E., Matysik-Wozniak, A., Sulborska, A., Polak, B., Dmitruk, M., Piotrowska-Weryszko, K., Stefanczyk, B. and Rejdak, R (2021) 'Histochemical and Phytochemical Analysis of Lamium album subsp. album L. Corolla: Essential Oil, Triterpenes, and Iridoids', Molecules, 26(14), pp. 4166. doi:10.3390/molecules26144166 Preclinical
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  6. Khanaki, K., Fekri, A., Abedinzade, M., Mohammadi, E. and Aghajanpour, F (2022) 'Potential anti-inflammatory effect of Lamium album extract through caspase-3 and cyclooxygenase-2 genes expression in a rat model of middle cerebral artery occlusion', Folia Medica, 64(2), pp. 275-282. doi:10.3897/folmed.64.e60562 Preclinical
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  13. Budzianowski, J. and Skrzypczak, L (1995) 'Phenylpropanoid esters from Lamium album flowers', 38(4), pp. 997--1001. doi:10.1016/0031-9422(94)00727-B Traditional / reference
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  14. Damtoft, S (1992) 'Iridoid glucosides from Lamium album', 31(1), pp. 175--178. doi:10.1016/0031-9422(91)83030-O Traditional / reference
    https://doi.org/10.1016/0031-9422(91)83030-O
  15. Pietrzak, W. and Nowak, R (2020) 'Lamalbid, Chlorogenic Acid, and Verbascoside as Tools for Standardization of Lamium album Flowers - Development and Validation of HPLC-DAD Method', 25(8). doi:10.3390/molecules25081913 Preclinical
    https://doi.org/10.3390/molecules25081913
  16. Grieve, M (1931). Available at: https://botanical.com/botanical/mgmh/n/netwhd11.html Traditional / reference
    https://botanical.com/botanical/mgmh/n/netwhd11.html
  17. Herbal Reality (n.d.) 'White Deadnettle (Lamium album): Benefits, Uses, Safety'. Available at: https://www.herbalreality.com/herb/white-deadnettle/ Traditional / reference
    https://www.herbalreality.com/herb/white-deadnettle/
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    https://scholar.google.com/scholar?q=Francis-Baker%2C%20T
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    https://www.ballyrobertgardens.com/products/lamium-album
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.